About 26 results found for searched term "ZY-1" (0.056 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2403 | Apoptosis Activator 2 | Caspase |
| 1-(3,4-Dichlorobenzyl)-1H-indole-2,3-dione | ||
| Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells. | ||
| M1364 | 1-Benzyl-1H-indole-2,3-dione | AChR/AChE |
| 1-Benzyl-1H-indole-2,3-dione | ||
| M9086 | NAD+ | Enzymes & Coenzymes |
| β-DPN; β-NAD; Coenzyme 1; Nadide；β-Nicotinamide Adenine Dinucleotide | ||
| NAD+, nicotinamide adenine dinucleotide, is a coenzyme that transfers hydrogen ions and is formed by the coupling of ribosylnicotinamide 5'-diphosphate to adenosine 5'-phosphate via pyrophosphate bonding.NAD+ is the oxidized form of NADH.NAD+ is a coenzyme that is formed by the coupling of ribosylnicotinamide 5'-diphosphate to adenosine 5 '-phosphate coupled by pyrophosphate bonding. | ||
| M9932 | Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine | Others |
| TBTA | ||
| Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine (TBTA) is a ligand that acts as a biochemical tool for the tagging of proteins and enzymes. | ||
| M11313 | Coenzyme Q10 | Metabolite/Endogenous Metabolite |
| CoQ10; Ubiquinone-10 | ||
| Coenzyme Q10 (CoQ10) forms the electron transport chain and participates in cellular aerobic respiration. | ||
| M20428 | Retigabine 2HCl | Potassium Channel |
| N-(2-amino-4-[fluorobenzylamino]-phenyl) carbamic acid (2HCl); D-23129 2HCl; Ezogabine 2HCl | ||
| Retigabine is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels. | ||
| M21613 | Recombinant Human UBE2V1 (E.coli, C-6His) | Recombinant Proteins |
| Ubiquitin-Conjugating Enzyme E2 Variant 1; UEV-1 | ||
| Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6, and TRAF2. It mediates transcriptional activation of target genes. UBE2V1 also controls the progress through the cell cycle and differentiation, the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. | ||
| M22462 | Recombinant Human UBE2D1 (E.coli, N-GST) | Recombinant Proteins |
| Ubiquitin-conjugating Enzyme E2 D1 | ||
| Recombinant Human UBE2D1 is produced by E.coli expression system and the target gene encoding Met1-Met147 is expressed with a GST tag at the N-terminus. Ubiquitin-conjugating enzyme E2 D1（UBE2D1）belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. | ||
| M22463 | Recombinant Human UBA1 Protein (Baculovirus-Insect, His & GST Tag) | Recombinant Proteins |
| Ubiquitin Activating Enzyme E1 | ||
| The recombinant human UBA1/GST chimera consists of 1294 amino acids and has a calculated molecular mass of 146 KDa. A DNA sequence encoding the human UBA1 (NP_003325.2) (Ser 2-Arg 1058) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. | ||
| M25103 | Ansuvimab | Anti-infection |
| zz-zyk mAb114 | ||
| Ansuvimab (Ansuvimab-zyk) is a recombinant human monoclonal IgG1 antibody that exhibits antiviral activity against Zaire ebolavirus. Ansuvimab binds to the glycoprotein on Zaire ebolavirus to block its entry into host cells. | ||
| M39065 | N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide | Metabolite/Endogenous Metabolite |
| N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide (Macamide impurity 10) is the impurity of Macamide. | ||
| M42587 | Enzyme-IN-1 | Proteasome |
| Enzyme-IN-1 is a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases. | ||
| M42596 | ZY-1 | Pyruvate Kinase |
| ZY-1 is a control molecule of ZY-2. | ||
| M42974 | Benzyl DC-81 | Others |
| Benzyl DC-81 is an anticancer agent with antiproliferative activity against A375 and MCF-7 cells. | ||
| M43842 | Tert-butyl 4-((1-((benzyloxy)carbonyl)piperidin-4-yl)methyl)piperazine-1-carboxylate | PROTAC Linker |
| 1-Piperazinecarboxylic acid, 4-[[1-[(phenylmethoxy)carbonyl]-4-piperidinyl]methyl]-, 1,1-dimethylethyl ester | ||
| Tert-butyl 4-((1-((benzyloxy)carbonyl)piperidin-4-yl)methyl)piperazine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs. | ||
| M43915 | 2,6-bis(benzyloxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | Ligand for E3 Ligase |
| 2,6-Bis(benzyloxy)pyridine-3-boronic Acid Pinacol Ester | ||
| 2,6-bis(benzyloxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | ||
| M44116 | (9Z,12Z)-N-Benzyloctadeca-9,12-dienamide | Others |
| (9Z,12Z)-N-Benzyloctadeca-9,12-dienamide | ||
| M44371 | 3-Oxo-4-benzyl-3,4-dihydro-1H-pyrrolo [2,1-c] oxazine-6-methylal | Others |
| 3-Oxo-4-benzyl-3,4-dihydro-1H-pyrrolo [2,1-c] oxazine-6-methylal | ||
| M49854 | 5-pirazynylo-1,3,4-tiadiazolo-2-tiol | Others |
| 5-pirazynylo-1,3,4-tiadiazolo-2-tiol | ||
| M52260 | (S)-1-Benzyl 2-methyl 4-oxopyrrolidine-1, 2-dicarboxylate | Amino Acid Derivatives |
| (S)-1-Benzyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate is a proline derivative. | ||
| M52294 | (S)-5-Benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride | Amino Acid Derivatives |
| (S)-5-Benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride is a glutamic acid derivative. | ||
| M54028 | (6S, 9S, 12S)-Benzyl 12-benzyl-9-isobutyl-2, 2-dimethyl-4, 7, 10-trioxo-6-phenethyl-3-oxa-5, 8, 11-triazatridecan-13-oate | Amino Acid Derivatives |
| (6S,9S,12S)-Benzyl 12-benzyl-9-isobutyl-2,2-dimethyl-4,7,10-trioxo-6-phenethyl-3-oxa-5,8,11-triazatridecan-13-oate is a phenylalanine derivative. | ||
| M54146 | N-Benzyloxycarbonyl-L-glutamic acid 1-methyl ester | Amino Acid Derivatives |
| N-Benzyloxycarbonyl-L-glutamic acid 1-methyl ester is a glutamic acid derivative. | ||
| M54586 | ZYT-1 | Thyroid Hormone Receptor |
| ZYT-1 is a thyroid receptor (THR-β) agonist. | ||
| M54866 | Recombinant Human USP14 (E.coli, N-6His) | Recombinant Proteins |
| Ubiquitin Carboxyl-Terminal Hydrolase 14; Deubiquitinating Enzyme 14 | ||
| USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. | ||
| M55197 | CID1231538 | GPR/FFAR |
| CID1231538 is a potent GPR35 antagonist, with IC50 of 0.55 μM. CID1231538 is a benzothiazole analogue. | ||
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