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Recombinant Human UBE2V1 (E.coli, C-6His)

Cat. No. M21613

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human UBE2V1 (E.coli, C-6His) Structure
Synonym:

Ubiquitin-Conjugating Enzyme E2 Variant 1; UEV-1

Size Price Availability Quantity
10ug USD 150  USD150 In stock
50ug USD 230  USD230 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1.0 EU/µg
  • COA
  • MSDS
Biological Activity

Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6, and TRAF2. It mediates transcriptional activation of target genes. UBE2V1 also controls the progress through the cell cycle and differentiation, the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Recombinant Human Ubiquitin-Conjugating Enzyme E2 Variant 1 is produced by E.coli expression system and the target gene encoding Ala2-Asn147 is expressed with a 6His tag at the C-terminus.

Chemical Information
Solubility (25°C) Water
Saline
PBS
Storage Store at ≤ -70°C, stable for 6 months after receipt
References

[1] Joanna Liwocha, et al. Nat Chem Biol. Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

[2] Rebecca J Burge, et al. PLoS Pathog. Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex

[3] Tatsuya Sawasaki, et al. Methods Mol Biol. Cell-free-based protein microarray technology using agarose/DNA microplate

[4] Sachiko Tsukamoto, et al. Bioorg Med Chem Lett. Leucettamol A: a new inhibitor of Ubc13-Uev1A interaction isolated from a marine sponge, Leucetta aff. microrhaphis

[5] M L Rothofsky, et al. Gene. CROC-1 encodes a protein which mediates transcriptional activation of the human FOS promoter

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Keywords: Recombinant Human UBE2V1 (E.coli, C-6His), Ubiquitin-Conjugating Enzyme E2 Variant 1; UEV-1 supplier, Cytokines and Growth Factors, inhibitors, activators

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