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Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6, and TRAF2. It mediates transcriptional activation of target genes. UBE2V1 also controls the progress through the cell cycle and differentiation, the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Recombinant Human Ubiquitin-Conjugating Enzyme E2 Variant 1 is produced by E.coli expression system and the target gene encoding Ala2-Asn147 is expressed with a 6His tag at the C-terminus.
| Solubility (25°C) | Water Saline PBS |
| Storage | Store at ≤ -70°C, stable for 6 months after receipt |
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