About 8 results found for searched term "SN-38" (0.109 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3016 | SN-38 | Topoisomerase |
| NK012; 7-ethyl-10-hydroxycamtothecin | ||
| SN-38 is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. | ||
| M3211 | Ondansetron | 5-HT Receptor |
| SN 307; GR 38032F; GR-C507/75 | ||
| Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. | ||
| M9655 | CL2A-SN-38 | Drug-Linker Conjugates for ADC |
| CL2A-SN38 | ||
| CL2A-SN-38 is a SN38 derivative with a peptide-linker which can easily react with antibody to form an ADC. | ||
| M24697 | Labetuzumab govitecan | Drug-Linker Conjugates for ADC |
| IMMU 130 hMN-14-SN-38 | ||
| Labetuzumab govitecan (IMMU 130) is an Anti-CEACAM5/SN-38 antibody-drug conjugate (ADC). Labetuzumab govitecan consists of the antibody Labetuzumab, SN-38, and a pH-sensitive Linker. Labetuzumab govitecan can be used for research of cancers, such as colorectal cancer. | ||
| M28881 | Mc-VC-PAB-SN38 | Drug-Linker Conjugates for ADC |
| Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs). | ||
| M42973 | SN-38-CO-DMEDA TFA | Others |
| SN-38-CO-DMEDA TFA is the intermediate product for synthesizing antibody-conjugated drug LND1035. | ||
| M56623 | SN-38 glucuronide | Metabolite/Endogenous Metabolite |
| SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan and has toxic effects on the gastrointestinal tract. | ||
| M55738 | MC-SN38 | Drug-Linker Conjugates for ADC |
| MC-SN38 is a agent-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody agent conjugate (ADC). | ||
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