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 About 3 results found for searched term "Rolipram" (0.123 seconds)

Cat.No.  Name Target
M3375 S-(+)-Rolipram PDE
(+)-Rolipram; (S)-Rolipram
S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
M5939 Rolipram PDE
ZK-62711, SB 95952
A selective inhibitor of PDE4, Rolipram, inhibits immunopurified PDE4B and PDE4D activity with IC50 of 130 nM and 240 nM, respectively. It has anti-inflammatory activity. Rolipram also increased cAMP levels and activated PKA, which in turn increased proteasome activity and inhibited tau aggregation.
M14499 (R)-(-)-Rolipram PDE
(R)-Rolipram; (-)-Rolipram
(R)-(-)-Rolipram is the R-enantiomer of Rolipram. Rolipram is a selective inhibitor of phosphodiesterases PDE4 with IC50 of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.



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