About 3 results found for searched term "Rolipram" (0.133 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3375 | S-(+)-Rolipram | PDE |
| (+)-Rolipram; (S)-Rolipram | ||
| S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer. | ||
| M5939 | Rolipram | PDE |
| ZK-62711, SB 95952 | ||
| A selective inhibitor of PDE4, Rolipram, inhibits immunopurified PDE4B and PDE4D activity with IC50 of 130 nM and 240 nM, respectively. It has anti-inflammatory activity. Rolipram also increased cAMP levels and activated PKA, which in turn increased proteasome activity and inhibited tau aggregation. | ||
| M14499 | (R)-(-)-Rolipram | PDE |
| (R)-Rolipram; (-)-Rolipram | ||
| (R)-(-)-Rolipram is the R-enantiomer of Rolipram. Rolipram is a selective inhibitor of phosphodiesterases PDE4 with IC50 of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively. | ||
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