About 15 results found for searched term "R18" (0.052 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3541 | Miconazole Nitrate | Antibiotic |
| R18134 nitrate | ||
| Miconazole Nitrate is an imidazole antifungal agent that is used topically and by intravenous infusion. | ||
| M5787 | Miconazole | Antibiotic |
| R18134 | ||
| Miconazole (Monistat) is an imidazole antifungal agent. | ||
| M6141 | NIBR189 | GPR/FFAR |
| NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional). | ||
| M8559 | SR1848 | Others |
| SR1848 is a cell penetrant and potent inhibitor of orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) that reduces the expression of CyclinD1 and E1, which results in inhibition of cell proliferation. | ||
| M9468 | SR-18292 | PPAR |
| SR18292 | ||
| SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor, which increases PGC-1α acetylation, suppresses gluconeogenic gene expression. | ||
| M15108 | FR183998 free base | Na+/H+ Exchanger (NHE) |
| FR183998 free base is a potent Na+/H+-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively. | ||
| M20704 | SR18662 | Others |
| SR18662 is an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM. SR18662 reduces the viability of multiple colorectal cancer cell lines. SR18662 induces apoptosis. | ||
| M27763 | Migalastat | Others |
| GR181413A free base | ||
| Migalastat (GR181413A free base) is an orally active and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC50 of 0.04 μM for human α-Gal A. | ||
| M29680 | SR18662 | KLF |
| SR18662 is a potent inhibitor of Krüppel-like factor five (KLF5) with an IC50 of 4.4 nM and an analogue of ML264 with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer. | ||
| M30575 | Migalastat hydrochloride | Others |
| DGJ; 1-Deoxygalactonojirimycin; GR181413A | ||
| Migalastat hydrochloride (DGJ; 1-Deoxygalactonojirimycin; GR181413A) is a potent and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC50 of 0.04 μM for human α-Gal A. | ||
| M30950 | SMER18 | Autophagy |
| SMER18 is a small molecule enhancer of rapamycin which act as a mTOR-independent autophagy inducer. Target: mTOR SMER18 induces autophagy independently of Rapamycin in mammalian cells, enhancing the clearance of autophagy substrates such as mutant huntingtin and A53T alpha-synuclein, which are associated with Huntington's disease and familial Parkinson's disease, respectively. SMER18 acts either independently or downstream of the target of Rapamycin, attenuates mutant huntingtin-fragment toxicity in Huntington's disease cell and Drosophila melanogaster models, which suggests therapeutic potential. | ||
| M41907 | FR181157 | Prostaglandin Receptor |
| FR181157, an orally active PGI2 agonist activity with especially good pharmacokinetic properties. | ||
| M44633 | Raddeanoside R18 | Others |
| Raddeanoside R18 | ||
| M52812 | R18 | Raf |
| R18 is a peptide antagonists of 14-3-3, with a KD of 70-90 nM. | ||
| M56528 | SSR180711 hydrochloride | AChR/AChE |
| SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
