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SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor, which increases PGC-1α acetylation, suppresses gluconeogenic gene expression. SR-18292 reduces blood glucose, strongly increases hepatic insulin sensitivity, and improves glucose homeostasis in dietary and genetic mouse models of T2D.
*The compound is unstable in solutions, freshly prepared is recommended.
| Molecular Weight | 366.50 |
| Formula | C23H30N2O2 |
| CAS Number | 2095432-55-4 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | -20°C, dry, sealed |
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