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Migalastat hydrochloride

Cat. No. M30575

All AbMole products are for research use only, cannot be used for human consumption.

Migalastat hydrochloride Structure
Synonym:

DGJ; 1-Deoxygalactonojirimycin; GR181413A

Size Price Availability Quantity
1mg USD 40  USD40 In stock
5mg USD 90  USD90 In stock
10mg USD 137  USD137 In stock
25mg USD 275  USD275 In stock
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Quality Control & Documentation
Biological Activity

Migalastat hydrochloride (DGJ; 1-Deoxygalactonojirimycin; GR181413A) is a potent and competitive inhibitor of α-galactosidase A (α-Gal A) with an IC50 of 0.04 μM for human α-Gal A.

Chemical Information
Molecular Weight 199.63
Formula C6H14ClNO4
CAS Number 75172-81-5
Form Solid
Solubility (25°C) Water ≥ 200 mg/mL
Storage 4°C, dry, sealed
References

[1] Maurizio Pieroni, et al. J Am Coll Cardiol. Cardiac Involvement in Fabry Disease: JACC Review Topic of the Week

[2] M Michaud, et al. Rev Med Interne. [Fabry disease: A review]

[3] Sanne J van der Veen, et al. J Inherit Metab Dis. Developments in the treatment of Fabry disease

[4] Emma H McCafferty, et al. Drugs. Migalastat: A Review in Fabry Disease

[5] Dominique P Germain, et al. N Engl J Med. Treatment of Fabry's Disease with the Pharmacologic Chaperone Migalastat

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Keywords: Migalastat hydrochloride, DGJ; 1-Deoxygalactonojirimycin; GR181413A supplier, inhibitors, activators

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