About 13 results found for searched term "Psoralen" (0.053 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2450 | Bergapten | Autophagy |
| 5-Methoxypsoralen | ||
| Bergapten is a psoralen that can be photoactivated and is capable of crossing-linking DNA, covalently modifying proteins and lipids, and consequently inhibiting cell replication. | ||
| M3351 | Methoxsalen | Others |
| 8-Methoxypsoralen; Xanthotoxin; 8-MOP | ||
| Methoxsalen (Oxsoralen) a naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia, is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight. | ||
| M4367 | Xanthotoxol | 5-HT Receptor |
| 8-Hydroxypsoralen | ||
| Xanthotoxol (8-hydroxypsoralen) is a bioactive linear furan coumarin with strong pharmacological activities such as anti-inflammatory, antioxidant, 5-HT antagonist and neuroprotective effects. | ||
| M4478 | Psoralen | DNA/RNA Synthesis |
| Ficusin; Furocoumarin | ||
| Psoralen(Furocoumarin) is an active ingredient from Fructus Psoraleae; has anticancer activity. | ||
| M4479 | Isopsoralen | Anti-infection |
| Angelicin | ||
| Isopsoralen (Angelicin) is a furocoumarin naturally occurring tricyclic aromatic compound which has anti-cancer, antiviral, anti-inflammatory activity. | ||
| M6039 | Trioxsalen | DNA Alkylator/Crosslinker |
| Trisoralen; Trioxysalen; Trimethylpsoralen; TMP | ||
| Trioxsalen is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death. | ||
| M10656 | Bergaptol | Cytochrome P450 (e.g. CYP17) |
| 4-Hydroxybergapten; 5-Hydroxypsoralen | ||
| Bergaptol is a hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 uM. | ||
| M14258 | PAP-1 | Potassium Channel |
| 5-(4-Phenoxybutoxy)psoralen | ||
| PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a potent, selective, and orally active Kv1.3 blocker (EC50=2 nM). | ||
| M14310 | Bergamottin | Cytochrome P450 (e.g. CYP17) |
| 5-Geranoxypsoralen; Bergamotine; Bergaptin | ||
| Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM. | ||
| M16271 | 8-Geranyloxypsoralen | Coumarins |
| 8-Geranyloxypsoralen | ||
| M18191 | 5-Hydroxy-8-methoxypsoralen | Others |
| 5-Hydroxy-8-methoxypsoralen | ||
| M18597 | Isopsoralenoside | Others |
| Isopsoralenoside is a benzofuran glycoside from Psoralea corylifolia. Isopsoralenoside show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity. | ||
| M18872 | Psoralenoside | Others |
| Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol). Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity. | ||
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