About 4 results found for searched term "Paclitaxel-d5" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M55442 | Paclitaxel-d5 | Microtubule |
| Paclitaxel-d5 | ||
| M1970 | Paclitaxel | Microtubule |
| Taxol; NSC 125973 | ||
| Paclitaxel is a diterpenoid derived from the bark of the plant Picea abies, and is also a microtubule polymer stabilizer, which promotes polymerization of microtubule proteins to inhibit depolymerization, maintains the stability of microtubule proteins, and inhibits cellular mitosis, and acts on human endothelial cells with an IC50 of 0.1 pM. | ||
| M30332 | ZINC05007751 | Others |
| ZINC05007751 is a potent NIMA-related kinase NEK6 inhibitor with an IC50 of 3.4 μM. ZINC05007751 shows antiproliferative activity against a panel of human cancer cell lines, and displays a synergistic effect with Cisplatin and Paclitaxel in a BRCA2 mutated ovarian cancer cell line. ZINC05007751 is very selective against NEK1 and NEK6 with no significant activity was observed against NEK2, NEK7, and NEK9. | ||
| M31338 | ANG1005 | Others |
| Paclitaxel trevatide | ||
| ANG1005 is a paclitaxel derivative as well as a peptide-coupled compound (PDC) consisting of three paclitaxel and Angiopep-2 covalently linked. In addition, ANG1005 is a modulator of LDLR and an inhibitor of mitosis and microtubule proteins. | ||
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