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 About 7 results found for searched term "Paclitaxel" (0.032 seconds)

Cat.No.  Name Information
M1940 Docetaxel Docetaxel (Taxotere), a semi-synthetic analog of paclitaxel (Taxol), is a promoter of microtubule polymerization leading to cell cycle arrest at G2/M, apoptosis and cytotoxicity.
M1970 Paclitaxel Paclitaxel is a mitotic inhibitor with IC50 of 0.1 pM in human endothelial cells.
M3901 Combretastatin A4 Combretastatin A4 (CA-4), which is a natural stilbene isolated from Combretum caffrum, is a microtubule-destabilizing agent that binds to the colchicine domain on β-tubulin and exhibits a lower toxicity profile than paclitaxel or the Vinca alkaloids.
M4857 Epothilone B Epothilone B (EPO906, Patupilone) is a paclitaxel-like microtubule-stabilizing agent with EC0.01 of 1.8 μM.
M5039 10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility.
M8493 NSC756093 NSC756093, a podophyllotoxin analog, is a potent and specific inhibitor of GBP1:PIM1 interaction that inhibits proliferation of paclitaxel resistant cancer cells.
M8641 LP117 LP117 is a pirinixic acid derivative that interferes with ATP-binding cassette (ABC) transporter ABCB1-mediated substrates transport, including vincristine, vinorelbine, paclitaxel, and actinomycin D, but not doxorubicin, rhodamine 123, or JC-1.

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