About 4 results found for searched term "Nigericin" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7029 | Nigericin sodium salt | Potassium Channel |
| Sodium Nigericin | ||
| Nigericin (NSC 292567) sodium salt is a selective K+ ionophore, Nigericin sodium salt is also an NLRP3 activator which can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes. | ||
| M9780 | Nigericin | Potassium Channel |
| Antibiotic K178, Antibiotic X464 | ||
| Nigericin is an antibiotic derived from Streptomyces hygroscopicus, it acts as an H+, K+, Pb2+ ionophore. | ||
| M45372 | NLRP3/AIM2-IN-3 | NLR |
| NLRP3/AIM2-IN-3 is a potent inhibitor that interferes with the interaction of NLRP3 or AIM2 with the bridging protein ASC and inhibits ASC oligomerization, and has different species-specific effects on NLRP3 and AIM2 inflammasome-dependent pyroptosis. In addition, NLRP3/AIM2-IN-3 inhibited LPS/nigericin-stimulated cell pyroptosis in THP-1 macrophages with an IC50 of 0.077 ± 0.008 μM. | ||
| M54573 | NLRP3-IN-NBC6 | NLR |
| NLRP3-IN-NBC6 is a potent and selective NLRP3 inflammatory vesicle inhibitor (IC50= 574 nM) that acts independently of Ca2+.NLRP3-IN-NBC6 inhibits Nigericin-induced inflammatory responses in THP-1 cells and Imiquimod-induced LPS-primed bone marrow-derived macrophages ( BMDMs) release of IL-1β. | ||
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