NLRP3 Inflammasome Inhibitor I - Search Results

About 6 results found for searched term "NLRP3 Inflammasome Inhibitor I" (0.127 seconds)

Cat.No.	Name	Target
M20412	NLRP3 Inflammasome Inhibitor I	Immunology/Inflammation
	NLRP3-IN-2
	NLRP3 Inflammasome Inhibitor I, an intermediate substrate in the synthesis of glyburide which is free of the cyclohexylurea moiety involved in insulin release, is a novel inhibitor of the NLRP3 inflammasome.
M4578	Oridonin	NLR
	Isodonol；NSC-250682
	Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity. Oridonin (NSC-250682) also acts as an inhibitor of AKT, with IC50 values of 8.4 and 8.9 μM for AKT1 and AKT2, respectively.
M30795	INF4E	NLR
	INF4E is a potent NLRP3 inflammasome inhibitor. INF4E inhibits caspase-1 and NLRP3 ATPase activities. INF4E shows protection against the IR-induced myocardial injury and dysfunction.
M30978	Fc 11a-2	NLR
	Fc 11a-2, a benzimidazole compound, is an orally active and potent NLRP3 inflammasome inhibitor. Fc 11a-2 restrains the formation of NLRP3 inflammasome by inhibiting activation of caspase-1 and thus the activation of IL-1b/IL-18. Fc 11a-2 prevents the development of Dextran sulfate sodium (DSS)-induced murine experimental colitis.
M42016	NLRP3-IN-17	NLR
	NLRP3-IN-17 is a potent, selective and orally active NLRP3 inflammasome inhibitor with an IC50 value of 7 nM.
M56385	NBC19	NLR
	NBC19 is an NLRP3 inflammasome inhibitor with an IC50 of 60 nM in differentiated THP1 cells.