About 20 results found for searched term "NADH" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4989 | NADH | Enzymes & Coenzymes |
| beta-NADH disodium salt | ||
| NADH disodium salt is a coenzyme of a large number of oxidoreductases. | ||
| M50299 | NADH oxidase | Enzymes & Coenzymes |
| NADH oxidase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M6209 | Rotenone | Animal Modeling |
| NSC26258 | ||
| Rotenone is an inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase, and is used to induce a Parkinson-like syndrome as an experimental model in rats. | ||
| M9086 | NAD+ | Enzymes & Coenzymes |
| β-DPN; β-NAD; Coenzyme 1; Nadide；β-Nicotinamide Adenine Dinucleotide | ||
| NAD+, nicotinamide adenine dinucleotide, is a coenzyme that transfers hydrogen ions and is formed by the coupling of ribosylnicotinamide 5'-diphosphate to adenosine 5'-phosphate via pyrophosphate bonding. NAD+ is the oxidized form of NADH. NAD+ is a coenzyme that is formed by the coupling of ribosylnicotinamide 5'-diphosphate to adenosine 5 '-phosphate coupled by pyrophosphate bonding. | ||
| M10336 | KL1333 | Mitochondrial Related |
| NQO1 activator 1 | ||
| KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. | ||
| M14660 | BI-4916 | PHGDH |
| BI-4916 is a prodrug of BI-4924. BI-4924 is a NADH/NAD+-competitive PHGDH inhibitor. | ||
| M19954 | Phenazine methosulfate | Antibiotic |
| N-Methylphenazonium methosulfate; 5-Methylphenazinium methyl sulfate | ||
| Phenazine methosulfate is widely used as an intermediate electron carrier for coupling the production of NADH or NADPH to the reduction of tetrazolium salts to coloured formazans. | ||
| M20706 | HQNO | Others |
| 2-heptyl-4-hydroxyquinoline-N-oxide | ||
| HQNO is a natural quinolone secreted by P. aeruginosa. HQNO is a potent inhibitor of the electron transport chain with Kd of 64 nM for the ubiquinol-ferricytochrome c oxidoreductase segment (Complex III) of the respiratory chain. HQNO is also an inhibitor of bacterial and mitochondrialType II NADH : quinone oxidoreductase (NDH-2) with IC50 of 7.3 μM in the presence of 50μM menadione. | ||
| M22493 | sn-Glycerol 3-phosphate | Metabolite/Endogenous Metabolite |
| sn-Glycerol 3-phosphate is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis. | ||
| M25491 | Malic Dehydrogenase | Enzymes & Coenzymes |
| Malic Dehydrogenase (MDH) is a ubiquitous enzyme, it plays an important role in the citric acid cycle in mitochondria. It catalyzes the interconversion of substrates malate and oxaloacetate with the simultaneous oxidation/reduction of NAD/NADH+. | ||
| M28552 | WST-1 | Cell Analysis |
| WST-1 is a kind of water-soluble tetrazolium salt. WST induces the intracellular mitochondrial dehydrogenase to conduct NADH-dependent enzyme digestion reaction, releasing the water-soluble methyl benzene product. WST-1 can be used for the detection of cell proliferation and cytotoxicity, via the determination of the light absorption value at 450 nm. | ||
| M28689 | NITD-916 | Antibiotic |
| NITD-916, a 4-hydroxy-2-pyridone derivative, is an orally active and highly lipophilic mycobacterial enoyl reductase InhA inhibitor with an IC50 of 570 nM. NITD-916 forms a ternary complex with InhA and NADH to block access to the fatty acyl substrate binding pocket. NITD-916 has potent anti-tuberculosis effects. | ||
| M28876 | RYL-552 | Mitochondrial Related |
| RYL-552, a mitochondrial electron transport chain (ETC) inhibitor, is a P. falciparum NADH dehydrogenase 2 (PfNDH2) inhibtor. | ||
| M29785 | Piericidin A | Antibiotic |
| AR-054 | ||
| Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity. | ||
| M30223 | WST-3 | Fluorescent Dye |
| WST-3 is a water-soluble tetrazolium dye. In the presence of an electron mediator, WST-3 is reduced to WST-3 formazan by NADH and displays an absorption maxima of 433 nM. | ||
| M38798 | Pyridaben | Parasite |
| Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function. | ||
| M40694 | RIG012 | Others |
| RIG012 is a potent RIG-I antagonist that blocks RIG-I-initiated signaling, inhibits transcriptional induction of CXCL10, IFN-β 1, and IRF9, and reduces IL6 mRNA levels. The IC50 was 0.71 μM when assayed with NADH-coupled ATPase. | ||
| M52607 | beta-Galactose dehydrogenase | Metabolite/Endogenous Metabolite |
| beta-Galactose dehydrogenase can make conversion of galactose to galactonolactone and the concomitant reduction of NAD to the fluorescent NADH. | ||
| M55218 | Aldehyde dehydrogenase | Enzymes & Coenzymes |
| ALDH | ||
| Aldehyde dehydrogenase is a soluble enzyme and its activity depends on potassium ions and cysteine. ALDH is a component of nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH) recycling systems. | ||
| M58460 | NAD sodium | Metabolite/Endogenous Metabolite |
| β-Nicotinamide adenine dinucleotide sodium salt | ||
| NAD sodium (β-Nicotinamide adenine dinucleotide sodium salt) is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP. | ||
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