Free shipping on all orders over $ 500

HQNO

Cat. No. M20706

All AbMole products are for research use only, cannot be used for human consumption.

HQNO Structure
Synonym:

2-heptyl-4-hydroxyquinoline-N-oxide

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.

Quality Control & Documentation
Biological Activity

HQNO is a natural quinolone secreted by P. aeruginosa. HQNO is a potent inhibitor of the electron transport chain with Kd of 64 nM for the ubiquinol-ferricytochrome c oxidoreductase segment (Complex III) of the respiratory chain. HQNO is also an inhibitor of bacterial and mitochondrialType II NADH : quinone oxidoreductase (NDH-2) with IC50 of 7.3 μM in the presence of 50μM menadione.

Chemical Information
Molecular Weight 259.34
Formula C16H21NO2
CAS Number 341-88-8
Solubility (25°C) DMSO 9 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jiao Mo, et al. Int J Parasitol Drugs Drug Resist. Effect of the pseudomonas metabolites HQNO on the Toxoplasma gondii RH strain in vitro and in vivo

[2] Jessica Petri, et al. Biochim Biophys Acta Bioenerg. Structure of the NDH-2 - HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors

[3] Jiwon Kang, et al. J Biochem Mol Biol. HQNO-sensitive NADH:quinone oxidoreductase of Bacillus cereus KCTC 3674

[4] G Van Ark, et al. Biochim Biophys Acta. Binding of HQNO to beef-heart sub-mitochondrial particles

Related Products
DSPE-PEG-FA

DSPE-PEG2K-FA is a PEG derivative containing folic acid. DSPE-PEG2K-FA has a targeting effect and can bind to folic acid receptors in cancer cells. DSPE-PEG2K-FA forms micelles/lipid bilayers and can be used in research on targeted drug delivery systems.
Lifastuzumab

Lifastuzumab is a humanized anti-NaPi2b IgG1 monoclonal antibody.
GPVI antagonist 1

GPVI antagonist 1 is a glycoprotein VI (GPVI) platelet receptor antagonist. GPVI antagonist 1 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM.
MPSD TFA

MPSD TFA (MARCKS-ED TFA) is a 25-amino acid peptide based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate (MARCKS). MPSD TFA can sense membrane curvature and recognize phosphatidylserine. MPSD TFA can be utilized as biological probe to study membrane shape and lipid composition.
4-Nitro-2,1,3-benzoselenadiazole

4-Nitro-2,1,3-benzoselenadiazole is a biochemical material that can be used in scientific research.
  Catalog
Abmole Inhibitor Catalog




Keywords: HQNO, 2-heptyl-4-hydroxyquinoline-N-oxide supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.