About 22 results found for searched term "MCI" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1716 | Gemcitabine Hydrochloride | DNA/RNA Synthesis |
| Gemzar, LY-188011 | ||
| Gemcitabine (Gemzar, LY188011) inhibits DNA synthesis with an IC50 of 0.06 µM. | ||
| M2251 | Edaravone | ROS |
| MCI-186 | ||
| Edaravone is a radical scavenger and antioxidant which is able to protect against the effects of ischemia. | ||
| M3465 | Triamcinolone | Others |
| Triamcinolone is a long-acting corticosteroid. Triamcinolone is a corticosteroid hormone receptor (GCR) agonist and an anti-inflammatory agent. | ||
| M3508 | Triamcinolone Acetonide | GCR |
| Triamcinolone Acetonide is a more potent type of triamcinolone, being about 8 times as effective as prednisone. | ||
| M5637 | Famciclovir | Anti-infection |
| BRL-42810 | ||
| Famciclovir is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections. | ||
| M5680 | Gemcitabine | DNA/RNA Synthesis |
| NSC 613327; LY188011 | ||
| Gemcitabine (LY-188011; NSC 613327) is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagyand apoptosis. | ||
| M5951 | Sarpogrelate HCl | 5-HT Receptor |
| MCI-9042 | ||
| Sarpogrelate (MCI-9042) hydrochloride, a selective 5-HT2 antagonist, with pKis of 8.52, 6.57, and 7.43 for 5-HT2A, 5-HT2B, and 5-HT2C receptors, respectively. | ||
| M9210 | Ampicillin | Antibiotic |
| Ampicillin acid; Principen; Amcill | ||
| Ampicillin is an antibiotic against a variety of gram-positive and gram-negative bacteria. | ||
| M13701 | Gemcitabine elaidate | Others |
| CP-4126; CO-101; Gemcitabine 5'-elaidate | ||
| Gemcitabine elaidate (CP-4126) is lipophilic pro-drug of Gemcitabine. Gemcitabine elaidate is converted to Gemcitabine by esterases in order to be phosphorylated. Gemcitabine elaidate exhibits anti-tumor activity. | ||
| M13702 | Gemcitabine elaidate hydrochloride | Others |
| CP-4126 hydrochloride; CO-101 hydrochloride; Gemcitabine 5'-elaidate hydrochloride | ||
| Gemcitabine elaidate (CP-4126) hydrochloride is lipophilic pro-drug of Gemcitabine. Gemcitabine elaidate hydrochloride is converted to Gemcitabine by esterases in order to be phosphorylated. Gemcitabine elaidate hydrochloride exhibits anti-tumor activity. | ||
| M20396 | Argatroban | Thrombopoietin/Thrombin |
| MCI-9038 | ||
| Argatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant. | ||
| M20791 | Amcinonide | NO Synthase |
| Cyclocort, CL-34699 | ||
| Amcinonide (Cyclocort, CL-34699) is an inhibitor of nitric oxide (NO) release from activated microglia with IC50 of 3.38 nM. | ||
| M21775 | Amcinafal | Others |
| Amcinafal | ||
| M22186 | Deramciclane | Others |
| Deramciclane | ||
| M24588 | Demcizumab | Notch |
| OMP 21M18 Human Anti-TNFRSF10B Recombinant Antibody | ||
| Demcizumab (OMP 21M18) is an anti-DLL4 monoclonal antibody. Demcizumab is a potent inhibitor of the Notch pathway. Demcizumab alone or in combination with chemotherapy is effective in various cancer models. | ||
| M30381 | Bifemelane hydrochloride | Monoamine Oxidase |
| MCI-2016 | ||
| Bifemelane hydrochloride (MCI-2016) is a potent, selective and competitive inhibitor of monoamine oxidase A (MAO-A), with a Ki of 4.20 μM. Bifemelane hydrochloride also inhibits MAO-B noncompetitively with a Ki of 46.0 μM. Bifemelane hydrochloride has a potent antidepressant activity and can be used for the research of cognitive and emotional disturbances related to cerebrovascular disease. | ||
| M30845 | Bifemelane | Calcium Channel |
| MCI-2016 free base | ||
| Bifemelane is a nootropic compound. Bifemelan causes the first peak by stimulating release from intracellular Ca2+ stores and the second by capacitive entry through store–operated Ca2+ channels. Bifemelane will be provided as a pharmacological tool for basic studies on astrocytes. | ||
| M41437 | Tibremciclib | CDK |
| Tibremciclib is a CDK4 inhibitor with antineoplastic activity. | ||
| M42040 | MCI | ROS |
| MCI alleviates inflammation by macrophage reprogramming via targeting ROS scavenging and COX-2 downregulation. | ||
| M53690 | Dermcidin-1L (human) | Antibiotic |
| Dermcidin-1L (human) is an antibiotic peptide secreted by sweat glands. | ||
| M56002 | Gemcitabine elaidate hydrochloride | Nucleoside Antimetabolite/Analog |
| Gemcitabine elaidate (CP-4126) hydrochloride is lipophilic pro-agent of Gemcitabine. | ||
| M57783 | Famciclovir Impurity | Others |
| Famciclovir Impurity | ||
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