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Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1.
| Cell Experiment | |
|---|---|
| Cell lines | |
| Preparation method | |
| Concentrations | |
| Incubation time | |
| Animal Experiment | |
|---|---|
| Animal models | Male C57BL/6 mice |
| Formulation | dissolved in normal saline |
| Dosages | 200 mg/kg, daily for 5 days |
| Administration | intraperitoneally [i.p.] |
| Molecular Weight | 349.40 |
| Formula | C16H19N3O4S |
| CAS Number | 69-53-4 |
| Solubility (25°C) | DMSO 10 mM |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Chopra SL, et al. Can J Comp Med Vet Sci. Effect of Ampicillin on E. Coli of Swine Origin.
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