About 15 results found for searched term "MAO-B-IN-3" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42685 | MAO-B-IN-3 | Monoamine Oxidase |
| MAO-B-IN-3 is a reversible and selective MAO-B inhibitor (IC50=96 nM). | ||
| M3183 | Quinacrine dihydrochloride | Anti-infection |
| Mepacrine dihydrochloride; SN-390 | ||
| Quinacrine dihydrochloride is a non-selective MAO-A/B inhibitor. Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis. | ||
| M3341 | Selegiline hydrochloride | Monoamine Oxidase |
| Deprenyl hydrochloride | ||
| Selegiline (Deprenyl) hydrochloride is a potent, selective and irreversible inhibitor of MAO-B, with an IC50 of 51 nM. Selegiline hydrochloride exhibits 450-flod selectivity for MAO-B over MAO-A (IC50=23 μM). | ||
| M4531 | Rosiridin | Monoamine Oxidase |
| Rosiridin inhibits MAO A and MAO B and has A potential role in depression and alzheimer's disease. The inhibition rate of Rosiridin against MAO B at 10 μM was 83.8% (pIC50=5.38). | ||
| M14563 | 4-Hydroxyderricin | Monoamine Oxidase |
| 4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. | ||
| M14567 | Pargyline | Monoamine Oxidase |
| Pargyline is an irreversible monoamine oxidase (MAO) inhibitor with Kis of 13 μM and 0.5 μM for MAO-A and MAO-B, respectively. Pargyline has antihypertensive and anticancer activities. | ||
| M14568 | Rasagiline | Monoamine Oxidase |
| (R)-AGN1135; TVP1012 | ||
| Rasagiline (R-AGN1135) is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively. | ||
| M19461 | Eckol | Monoamine Oxidase |
| Eckol is a potent hMAO-A (Mixed) and hMAO-B (non-competitive) inhibitor with IC50s of 7.20 and 83.44 μM, respectively. Eckol shows antiallergic and antiviral effects. | ||
| M27684 | Lazabemide hydrochloride | Monoamine Oxidase |
| Ro 19-6327 hydrochloride | ||
| Lazabemide hydrochloride (Ro 19-6327 hydrochloride) is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM). Lazabemide inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease. | ||
| M28789 | hMAO-B-IN-4 | Monoamine Oxidase |
| hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research. | ||
| M29168 | Pirlindole mesylate | Monoamine Oxidase |
| Pirlindole mesylate is a selective and reversible MAO-A inhibitor. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3) . | ||
| M30356 | Pirlindole | Monoamine Oxidase |
| Pirlindole is a selective and reversible MAO-A inhibitor. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3). | ||
| M42674 | hAChE-IN-3 | Monoamine Oxidase |
| hAChE-IN-3 is a potent and blood-brain barrier permeable AChE, BuChE, MAO-B-IN-1 and BACE-1 inhibitor, with IC50 values of 0.44, 0.08, 5.15 and 0.38 μM, respectively. | ||
| M42675 | CHBO4 | Monoamine Oxidase |
| CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. | ||
| M42688 | MAO-B-IN-20 | Monoamine Oxidase |
| MAO-B-IN-20 is a potent MAO-B inhibitor with an IC50 of 0.037 μM. | ||
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