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Lazabemide hydrochloride

Cat. No. M27684

All AbMole products are for research use only, cannot be used for human consumption.

Lazabemide hydrochloride Structure
Synonym:

Ro 19-6327 hydrochloride

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Quality Control & Documentation
Biological Activity

Lazabemide hydrochloride (Ro 19-6327 hydrochloride) is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC50=0.03 μM) but less active for MAO-A (IC50>100 μM). Lazabemide  inhibits monoamine uptake at high concentrations, the IC50 values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease.

Chemical Information
Molecular Weight 236.1
Formula C8H11Cl2N3O
CAS Number 103878-83-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Xinkun Cheng, et al. J Inflamm (Lond). Components of the sympathetic nervous system as targets to modulate inflammation - rheumatoid arthritis synovial fibroblasts as neuron-like cells?

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  Catalog
Abmole Inhibitor Catalog




Keywords: Lazabemide hydrochloride, Ro 19-6327 hydrochloride supplier, Monoamine Oxidase, inhibitors, activators

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