About 20 results found for searched term "LYP-IN-4" (0.146 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42546 | LYP-IN-4 | Phosphatase |
| LYP-IN-4 is a reversible and selective inhibitor of lymphotyrosine phosphatase (LYP) (Ki=1.34 μM, IC50=3.52μM). | ||
| M2071 | ONX-0914 | Proteasome |
| PR-957 | ||
| Onx-0914 (PR-957) is a selective inhibitor of low molecular weight polypeptide 7 (LMP7), a chymotrypsin subunit of the immune proteasome. Onx-0914 blocks cytokine production and reduces the progression of experimental arthritis. Onx-0914 is a non-competitive irreversible inhibitor of mycobacterium proteasome (Ki=5.2 μM). Onx-0914 activates latent HIV-1 through HF-1-mediated p-TEFb activation. | ||
| M25536 | Recombinant Human CXCL13/BCA-1 (E. coli) | Cytokines and Growth Factors |
| CXC chemokine BLC; Small-inducible cytokine B13 | ||
| CXCL13, also known as B-lymphocyte chemoattractant (BLC), is a CXC chemokine that is constitutively expressed in secondary lymphoid organs. Recombinant human CXCL13 is a single non-glycosylated polypeptide chain containing 87 amino acids and mature human BCA-1 shares 64 % amino acid sequence similarity with the murine protein and 23–34 % amino acid sequence identity with other known CXC chemokines. Determined by a chemotaxis bioassay using human B cells, the biological activity is in a concentration range of 1.0-10 ng/ml. | ||
| M4519 | Procyanidin-B1 | TLR |
| Procyanidin B1 is a polyphenolic flavonoid that exists in common fruits and can bind to TLR4/MD-2 complex, showing anti-inflammatory activity. | ||
| M4599 | Arbutin | Others |
| p-Arbutin; β-Arbutin | ||
| Arbutin (β -arbutin) is a natural polyphenol isolated from the bear fruit plant Arctostaphylos uvaursi with antioxidant, anti-inflammatory and anti-tumor properties. It is a competitive inhibitor of tyrosinase in melanocytes, with a Kiapp value of 1.42 mM for monopholase. The value of p-diphenol enzyme Kiapp was 0.9 mM. Arbutin is also used as a bleaching agent. | ||
| M13447 | Recombinant Human IGF-II (E. coli) | Cytokines and Growth Factors |
| Insulin-like Growth Factor-II; Somatamedin A | ||
| Insulin-like Growth Factor II (IGF-II) is a 7 kDa single chain polypeptide with high homology to insulin. Protein structure：Expressed with an N-terminal Met. Igf-ii (ALA25-GLU91) , Accession # P01344-1. | ||
| M40683 | Recombinant Human RBP4 (HEK293, C-His) | Cytokines and Growth Factors |
| Retinol-Binding Protein 4 | ||
| Human-retinol binding protein is a single-chain polypeptide with a molecular weight of approximately 21000 and one binding site for retinol and other forms of vitamin A. In plasma, RBP4-retinol forms a complex with transthyretin (TTR), also known as thyroxine-binding protein and prealbumin. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision. | ||
| M21330 | H3K4(Me3) (1-20) | Peptides |
| H3K4(Me3) (1-20), a histone polypeptide, trimethylation of histone H3 to lysine 4 (H3K4 me3) is found in active euchromatin. Sequence: Ala-Arg-Thr-{Lys(Me3)}-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu. | ||
| M21425 | Recombinant Human MIF (E. coli) | Cytokines and Growth Factors |
| Macrophage Migration; Inhibitory Factor | ||
| Recombinant human macrophage migration inhibitor (rhMIF) is a single nonglycosylated polypeptide chain of 115 amino acids produced in Escherichia coli. Accession # P14174. | ||
| M25422 | Glypromate acetate | NMDA |
| Gly-Pro-Glu | ||
| Glypromate acetate is a neuroactive peptide with a potent action on acetylcholine release. Glypromate (Gly-Pro-Glu) is a weak NMDA receptor agonist binds to N-methyl-D-aspartate (NMDA) receptor with an IC50 value of 14.7 μM. | ||
| M28177 | Macrocarpal A | Antibiotic |
| 10-epi-Eucarobustol F | ||
| Macrocarpal A (10-epi-Eucarobustol F) is an antibacterial agent, which can be isolated from the leaves of Eucalyptus macrocarpa. Macrocarpal A inhibits the growth of Bacillus subtilis PCI219 (minimum inhibitory concentration below 0.2 µM) and Staphylococcus aureus FDA209P (minimum inhibitory concentration is 0.4 µM). | ||
| M31094 | Retatrutide acetate | Glucagon Receptor |
| LY3437943 acetate | ||
| Retatrutide (LY3437943) acetate is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide acetate inhibits for human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. | ||
| M39961 | Proanthocyanidin A4 | Others |
| Proanthocyanidin A4 is a polyphenol found in a variety of plants. Proanthocyanidin A4 possesses anti-inflammatory effects. | ||
| M41797 | Polyphemusin II-Derived Peptide | CXCR |
| Polyphemusin II-Derived Peptide (T140), a CXCR4 inhibitor, shows high inhibitory activity against HIV-1 entry. | ||
| M42544 | NC1 | Phosphatase |
| NC1 is a noncompetitive and allosteric lymphoid-specific tyrosine phosphatase (LYP) inhibitor, with a Ki value 4.3 μM. | ||
| M49466 | Retatrutide | Glucagon Receptor |
| LY3437943 | ||
| Retatrutide is a triple agonist peptide for glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) that binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. Retatrutide can be used in studies related to obesity. | ||
| M50423 | GIP (1-30) amide, porcine | Insulin Receptor |
| GIP (1-30) amide, porcine is a full glucose-dependent insulinotropic polypeptide (GIP) receptor agonist with high affinity equal to native GIP(1-42). | ||
| M51260 | Angiotensinogen (1-14) porcine | Others |
| Angiotensinogen (1-14) porcine is a polypeptide, which is the N-terminal fragment of angiotensinogen, including amino acid residues 1 to 14. | ||
| M53011 | Pancreatic Polypeptide, rat | Neuropeptide Receptor |
| Pancreatic Polypeptide, rat is an agonist of NPY receptor, with high affinity at NPYR4. | ||
| M54092 | Pancreatic Polypeptide, human | Neuropeptide Receptor |
| Pancreatic Polypeptide, human is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist. | ||
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