About 12 results found for searched term "IQ 1" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6662 | Demethylasterriquinone B1 | Insulin Receptor |
| Demethylasterriquinone B1 is a selective insulin RTK activator. | ||
| M6835 | IQ 1 | Wnt/beta-catenin |
| IQ 1 is a enables Wnt/β-catenin-driven expansion of ESCs; prevents spontaneous differentiation. | ||
| M8946 | IQ-1S | JNK |
| IQ-1 | ||
| IQ-1S is a potent and selective JNK inhibitor with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively. | ||
| M11313 | Coenzyme Q10 | Metabolite/Endogenous Metabolite |
| CoQ10; Ubiquinone-10 | ||
| Coenzyme Q10 (CoQ10) forms the electron transport chain and participates in cellular aerobic respiration. | ||
| M21613 | Recombinant Human UBE2V1 (E.coli, C-6His) | Cytokines and Growth Factors |
| Ubiquitin-Conjugating Enzyme E2 Variant 1; UEV-1 | ||
| Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6, and TRAF2. It mediates transcriptional activation of target genes. UBE2V1 also controls the progress through the cell cycle and differentiation, the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. | ||
| M22462 | Recombinant Human UBE2D1 (E.coli, N-GST) | Cytokines and Growth Factors |
| Ubiquitin-conjugating Enzyme E2 D1 | ||
| Recombinant Human UBE2D1 is produced by E.coli expression system and the target gene encoding Met1-Met147 is expressed with a GST tag at the N-terminus. Ubiquitin-conjugating enzyme E2 D1（UBE2D1）belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. | ||
| M22463 | Recombinant Human UBA1 Protein (Baculovirus-Insect, His & GST Tag) | Cytokines and Growth Factors |
| Ubiquitin Activating Enzyme E1 | ||
| The recombinant human UBA1/GST chimera consists of 1294 amino acids and has a calculated molecular mass of 146 KDa. A DNA sequence encoding the human UBA1 (NP_003325.2) (Ser 2-Arg 1058) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. | ||
| M28291 | TIQ-15 | CXCR |
| TIQ-15 is a potent CXCR4 antagonist with an IC50 value of 6 nM for CXCR4 Ca2+ flux. TIQ-15 inhibits CYP450 2D6 with an IC50 value of 0.32 μM. | ||
| M29059 | SJ-3366 | HIV Protease |
| IQP-0410 | ||
| SJ-3366 (IQP-0410) is a potent inhibitor of HIV nonnucleoside reverse transcriptase. SJ-3366 (IQP-0410) inhibits HIV at sub-nanomolar concentrations primarily through a typical non-nucleoside mechanism. | ||
| M42081 | SIQ17 | EGFR/HER2 |
| SIQ17 is an EGFR inhibitor that inhibits its activity by occupying the ATP-binding site, with IC50 of 0.62 nM. | ||
| M43421 | E3 ubiquitin ligase binder-1 | Ligand for E3 Ligase |
| E3 ubiquitin ligase binder-1 is a potent E3 ubiquitin ligase binder. | ||
| M54866 | Recombinant Human USP14 (E.coli, N-6His) | Cytokines and Growth Factors |
| Ubiquitin Carboxyl-Terminal Hydrolase 14; Deubiquitinating Enzyme 14 | ||
| USP14 belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. | ||
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