About 5 results found for searched term "IDE397" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43930 | Dalbavancin hydrochloride | Antibiotic |
| MDL-63397 hydrochloride; BI-397 hydrochloride;Dalvance hydrochloride | ||
| Dalbavancin hydrochloride is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria, and its MIC90 for inhibition of Staphylococcus aureus and Bacillus anthracis was 0.06 μg/mL and 0.25 μg/mL, respectively. | ||
| M55363 | IDE397 | Methionine Adenosyltransferase |
| GSK-4362676; MAT2A-IN-9 | ||
| IDE397 (GSK-4362676) is a potent, potential "first-in-class" inhibitor of methionine adenosyltransferase 2A (MAT2A). IDE397 (GSK-4362676) exhibits anti-tumor activity in MTAP-deleted PDX models. | ||
| M4741 | Harmine-hydrochloride | DYRK |
| Harmine Hydrochloride (Telepathine Hydrochloride) is a DYRK inhibitor with anticancer and anti-inflammatory activities. Harmine Hydrochloride has a high affinity for 5-HT2A serotonin receptor, with a Ki value of 397 nM. | ||
| M14884 | Pexidartinib hydrochloride | CSF-1R (c-Fms) |
| PLX-3397 hydrochloride | ||
| Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. | ||
| M28582 | Sibenadet hydrochloride | Dopamine Receptor |
| AR-C68397AA | ||
| Sibenadet hydrochloride (AR-C68397AA) is a dual D2 dopamine receptor, beta2-adrenoceptor agonist with bronchodilator activity. Investigation in animal models of key chronic obstructive pulmonary disease (COPD) symptoms has demonstrated that Sibenadet hydrochloride effectively inhibits sensory nerve activity, thereby reducing reflex cough, mucus production and tachypnoea. | ||
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