About 14 results found for searched term "Ginsenoside-F5" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4087 | Ginsenoside-F5 | Apoptosis |
| Ginsenoside F5, which was obtained from Panax ginseng, significantly inhibited the growth of HL-60 cells through apoptosis pathway. | ||
| M3987 | Ginsenoside Rb1 | Sodium Channel |
| Gynosaponin C; Gypenoside III | ||
| Ginsenoside Rb1 is an ingredient in the Chinese medicine Panax ginseng. Ginsenoside inhibition Na, K-ATPase++ activityIC50 6.3±1.0 μM. Ginsenoside Rb1 also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. | ||
| M4066 | Ginsenoside-Rb3 | NF-κB |
| Gypenoside IV | ||
| Ginsenoside Rb3 is derived from Panax Notoginseng. Ginsenoside Rb3 inhibited NF-κB transcriptional activity induced by TNFα in 293T cell lines with IC50 of 8.2 μM. Ginsenoside Rb3 also inhibited the induction of COX-2 and iNOS mRNA. | ||
| M4068 | Ginsenoside-Rg3 | Sodium Channel |
| 20(S)-Ginsenoside-Rg3; Rg3; S-Ginsenoside Rg3 | ||
| 20(S)-Ginsenoside Rg3 is the main ingredient of red ginseng. 20(S) -ginsenoside Rg3 inhibited Na+ and hKv1.4 channels with IC50 of 32.2±4.5 and 32.6±2.2 μM, respectively. 20(S) -ginsenoside Rg3 also inhibited Aβ, NF-κB activity and COX-2 expression. | ||
| M4072 | Ginsenoside-Rh3 | Keap1-Nrf2 |
| Ginsenoside Rh3 is a bacterial metabolite of Ginsenoside Rg5. Ginsenoside Rh3 induces Nrf2 activation in human retinal cells. | ||
| M4075 | Ginsenoside-Rd | NF-κB |
| Gypenoside VIII | ||
| Ginsenoside Rd inhibited NF-κB transcriptional activity induced by TNFα with IC50 of 12.05±0.82 μM. Ginsenoside Rd inhibited the expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibited CYP2D6, CYP1A2, CYP3A4 and CYP2C9 with IC50 of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM and 85.1±9.1 μM, respectively. | ||
| M4079 | (R)Ginsenoside-Rh2 | MMP |
| 20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as an anti-proliferative agent in cells. It has anticancer effects by blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis and has anti-inflammatory and antioxidant activities. 20(R)-Ginsenoside Rh2 inhibited the replication and proliferation of mouse and human γ herpevirus 68 (MHV-68) with an IC50 of 2.77 μM against mouse MHV-68. | ||
| M4080 | (R)Ginsenoside-Rg2 | Others |
| 20(R) -ginsenoside Rg2 is a Ginsenoside. 20(R)-Ginsenoside Rg2 has an inhibitory effect on lung cancer NCI-H1650 cells. It has anti-cancer activity. | ||
| M4081 | (R)Ginsenoside-Rg3 | Others |
| (20R)-Propanaxadiol; R-ginsenoside Rg3 | ||
| (20R) -Ginsenoside Rg3 ((20R)-Propanaxadiol), an active compound from ginseng root, has inhibitory effects on vascular endothelial cell proliferation (IC50= 10 nM) and antitumor activity. | ||
| M4089 | Ginsenoside-Ro | Calcium Channel |
| Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V; Ginsenoside-Ro | ||
| Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) has the antiplatelet effect of Ca2+ antagonist with IC50 of 155 μM. Ginsenoside Ro decreased TXA2 production and Ginsenoside Ro also slightly decreased COX-1 and TXAS activity. | ||
| M4090 | Ginsenoside-Rg5 | IGF-1R |
| Ginsenoside Rg5 is the main ingredient of red ginseng. Ginsenoside Rg5 blocks the binding of IGF-1 to its receptor with an IC50 of about 90 nM. Ginsenoside Rg5 also inhibited COX-2 mRNA expression by inhibiting DNA binding activity of NF-κB P65. | ||
| M4091 | Ginsenoside-Rg6 | NF-κB |
| Ginsenoside Rg6 inhibited NF-κB transcriptional activity induced by TNF-α in HepG2 cells with IC50 of 29.34 μM. Ginsenoside Rg6 also induced apoptosis. | ||
| M17765 | Ginsenoside Rk3 | NF-κB |
| Ginsenoside Rk3 significantly inhibits TNF-α-induced NF-κB transcriptional activity, with an IC50 of 14.24±1.30 μM in HepG2 cells. | ||
| M39971 | Vinaginsenoside R8 | Others |
| Vinaginsenoside R8, a triterpenoid glycoside isolated from the rhizomes of Panacis majoris. Vinaginsenoside R8 displays activities against adenosine diphosphate (ADP)-induced platelet aggregation (IC50=25.18 μM). | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
