About 17 results found for searched term "Factor Xa" (0.079 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1649 | Apixaban | Factor Xa |
| BMS-562247-01 | ||
| Apixaban is a highly selective, reversible and orally active direct factor Xa inhibitor with an IC50 of 0.22±0.02 µM. | ||
| M43947 | Enoxaparine | Thrombopoietin/Thrombin |
| Enoxaparine is a low molecular heparin that binds to antithrombin (AT) and accelerates its inhibition of factor Xa.Enoxaparine has a higher affinity for factor Xa than for thrombin, and its action on thrombin does not require HCII (heparin cofactor II). | ||
| M1776 | Rivaroxaban | Factor Xa |
| Xarelto, BAY 59-7939 | ||
| Rivaroxaban (Xarelto, BAY 59-7939) is oral direct factor Xa inhibitor with an IC50 value of 2.1nM. | ||
| M2597 | Betrixaban | Factor Xa |
| PRT-054021 | ||
| Betrixaban is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM(inhibition of Factor 10a). | ||
| M2661 | Edoxaban Tosylate Monohydrate | Factor Xa |
| DU-176b | ||
| Edoxaban is a selective factor Xa inhibitor with Ki of 0.561 nM, >10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant compound. | ||
| M3268 | BMS-740808 | Factor Xa |
| BMS-740808 is a highly potent, selective inhibitor of blood coagulation factor Xa (fXa) with Ki with 0.03 nM. | ||
| M7663 | Razaxaban hydrochloride | Others |
| Razaxaban is an orally available, potent and specific coagulation factor Xa inhibitor that reduces thrombus and fibrin formation. | ||
| M8109 | UK-371,804 HCl | Others |
| UK-371,804 is a reversible, substrate-competitive, highly potent (Ki = 10 nM) and selective urokinase-type plasminogen activator (uPA) Inhibitor with excellent selectivity over tPA, plasmin, Factor IXa and Xa. | ||
| M14428 | Edoxaban | Factor Xa |
| DU-176 | ||
| Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. | ||
| M14429 | Edoxaban tosylate | Factor Xa |
| DU-176b | ||
| Edoxaban tosylate (DU-176b) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. | ||
| M20478 | Betrixaban maleate | Factor Xa |
| Betrixaban maleate is a highly potent, selective, and orally efficacious factor Xa (fXa) inhibitor | ||
| M27846 | Fondaparinux sodium | Factor Xa |
| Fondaparin sodium; SR-90107A | ||
| Fondaparinux sodium is a synthetic pentasaccharide and indirect factor Xa inhibitor that mimics the structure of the heparin binding site and has a very high affinity for factor Xa, binding to AT and accelerating its inhibition of factor Xa. | ||
| M39138 | 5-R-Rivaroxaban | Factor Xa |
| 5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM). | ||
| M40247 | Garciniaxanthone E | Others |
| Garciniaxanthone E is a xanthone compound. Garciniaxanthone E significantly enhances cellular nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells. Garciniaxanthone E contributes to basic research and medicinal development in neurodegenerative diseases. | ||
| M42397 | EMD 495235 | Factor Xa |
| EMD 495235 is a potent and orally active coagulation factor Xa inhibitor with an IC50 of 5.5 nM and a Ki of 6.8 nM. | ||
| M42398 | FXIa-IN-13 | Factor Xa |
| FXIa-IN-13 is an Factor Xa inhibitor with antithrombotic activity. | ||
| M42606 | Benzamidine hydrochloride hydrate | Serine/Threonine Protease |
| Benzamidine hydrochloride hydrate is a reversible competitive trypsin-like serine proteases inhibitor with Kis of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin, uPA, Factor Xa, Thrombin and tPA, respectively. | ||
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