Free shipping on all orders over $ 500

Edoxaban Tosylate Monohydrate

Cat. No. M2661

All AbMole products are for research use only, cannot be used for human consumption.

Edoxaban Tosylate Monohydrate Structure


Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 70  USD70 In stock
5mg USD 44  USD44 In stock
10mg USD 62  USD62 In stock
25mg USD 90  USD90 In stock
50mg USD 118  USD118 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Edoxaban tosylate monohydrate is a selective factor Xa inhibitor with Ki of 0.561 nM, >10000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant compound.

Customer Product Validations & Biological Datas
Source Thromb Res (2015). Figure 2. Edoxaban
Method Calibrated automated thrombogram assays
Cell Lines pooled citrated platelet-poor plasma
Concentrations 25 to 250 ng/mL
Incubation Time 15 min
Results A direct linear correlation was observed between plasma concentrations of edoxaban and the blood coagulation parameters PT ratio and INR across all thromboplastin reagents
Source Thromb Res (2015). Figure 1. Edoxaban
Method Thrombin generation test
Cell Lines pooled citrated platelet-poor plasma
Concentrations 0.02-3.65 μM
Incubation Time 15 min
Results Accordingly, the values of distributions of peak thrombin over time were significantly different between edoxaban and fondaparinux at the tested molar concentration (0.9 μM)
Protocol (for reference only)
Cell Experiment
Cell lines
Preparation method
Incubation time
Animal Experiment
Animal models Venous stasis thrombosis model in rats and rabbits
Formulation 0.5% methylcellulose
Dosages 0.3–3 mg/kg (Rabbit); 0.5–12.5 mg/kg (Rat)
Administration p.o.
Chemical Information
Molecular Weight 738.27
Formula C24H30ClN7O4S.C7H8O3S.H2O
CAS Number 1229194-11-9
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month

[1] Bounameaux H, et al. Drugs. Edoxaban: an update on the new oral direct factor Xa inhibitor.

[2] Mikkaichi T, et al. Drug Metab Dispos. Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition.

Related Factor Xa Products
Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride

Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate.


D-Pro-Phe-Arg-Chloromethylketone, a inhibitor of coagulation factor XII and plasma kallikrein, plays an important role in thrombosis and inflammation.


Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin that can serve as a substrate for coagulation factors IXa (FIXa) and Xa (FXa).


Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination.


Delparantag (PMX-60056) is a salicylamide derivative and an effective unfractionated heparin (UFH) and low molecular weight heparin (LMWH) reversing agent.

Abmole Inhibitor Catalog

Keywords: Edoxaban Tosylate Monohydrate, DU-176b supplier, Factor Xa, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.