About 7 results found for searched term "Etoposide" (0.386 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2326 | Etoposide (VP-16-213) | Topoisomerase |
| VP-16-213; Vepesid; NSC 141540 | ||
| Etoposide (VP-16-213) is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity. | ||
| M13745 | Etoposide phosphate | Topoisomerase |
| BMY-40481 | ||
| Etoposide phosphate (BMY-40481) is a potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands. | ||
| M8406 | DDRI-18 | Others |
| DDRI-18 (DNA Damage Response Inhibitor-18) inhibits nonhomologous end-joining (NHEJ) DNA repair following double strand DNA breaks induced by ionizing radiation, and enhances the effects of DNA-damaging cancer drugs like etoposide, camptothecin and doxorubicin. | ||
| M8557 | CS1 | Others |
| CS1 is a selective and potent inhibitor of topoisomerase IIα (TopoIIα) that potently inhibits a proliferation of cancer cell lines including MDA-MB-231 and A548 cells, with less toxicity than etoposide. | ||
| M29392 | ARN-21934 | Topoisomerase |
| ARN-21934 is a potent, highly selective, blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II α over β. ARN-21934 inhibits DNA relaxation with an IC50 of 2 μM as compared to the anticancer agent Etoposide (IC50=120 μM). ARN-21934 exhibits a favorable in vivo pharmacokinetic profile and is a promising lead compound for anticancer research. | ||
| M30314 | Heptelidic acid | Caspase |
| Koningic acid | ||
| Heptelidic acid (Koningic acid) is a sesquiterpene antibiotic. Heptelidic acid inhibits Etoposide-induced apoptosis via downregulation of caspases. Koningic acid (KA) is a specific GAPDH inhibitor with an IC50of 90 μM. | ||
| M50899 | H-Gly-Leu-Phe-OH | Others |
| H-Gly-Leu-Phe-OH (GLF), an immunostimulatory tripeptide derived from α-lactalbumin, inhibits anticancer agent Etoposide-induced alopecia, epidermal thickening, and thinning of the adipocyte layer. | ||
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