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Etoposide phosphate

Cat. No. M13745

All AbMole products are for research use only, cannot be used for human consumption.

Etoposide phosphate Structure
Synonym:

BMY-40481

Price and Availability

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Quality Control & Documentation
Biological Activity

Etoposide phosphate (BMY-40481) is a potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands. Etoposide phosphate is the phosphate ester prodrug of etoposide and is considered as active equivalent to Etoposide. Etoposide phosphate induces cell cycle arrest, apoptosis, and autophagy.

Chemical Information
Molecular Weight 668.54
CAS Number 117091-64-2
Solubility (25°C) Water 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Winifred M Stockton, et al. J Oncol Pharm Pract. Etoposide and etoposide phosphate hypersensitivity in children: Incidence, risk factors, and prevention strategies

[2] Joel P Brooks, et al. J Oncol Pharm Pract. Etoposide phosphate for pediatric orthopedic malignancies after intravenous etoposide hypersensitivity

[3] K R Hande. Eur J Cancer. Etoposide: four decades of development of a topoisomerase II inhibitor

[4] L Schacter. Semin Oncol. Etoposide phosphate: what, why, where, and how?

[5] A H Witterland, et al. Pharm World Sci. Etoposide phosphate, the water soluble prodrug of etoposide

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  Catalog
Abmole Inhibitor Catalog




Keywords: Etoposide phosphate, BMY-40481 supplier, Topoisomerase, inhibitors, activators

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