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Etoposide phosphate (BMY-40481) is a potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor to prevent re-ligation of DNA strands. Etoposide phosphate is the phosphate ester prodrug of etoposide and is considered as active equivalent to Etoposide. Etoposide phosphate induces cell cycle arrest, apoptosis, and autophagy.
Molecular Weight | 668.54 |
CAS Number | 117091-64-2 |
Solubility (25°C) | Water 90 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] K R Hande. Eur J Cancer. Etoposide: four decades of development of a topoisomerase II inhibitor
[4] L Schacter. Semin Oncol. Etoposide phosphate: what, why, where, and how?
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