About 13 results found for searched term "EAAT" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6900 | LDN 212320 | EAAT |
| LDN/OSU-0212320; LDN-0212320; OSU-0212320 | ||
| LDN 212320 is a increases EAAT2 expression; neuroprotective. | ||
| M7451 | UCPH 101 | Others |
| UCPH 101 is a selective non-substrate EAAT1 inhibitor. | ||
| M8671 | UCPH-102 | Others |
| UCPH-102 is a selective inhibitor of the Excitatory Amino Acid Transporter subtype-1 (EAAT1, GLAST) with an IC50 value of 420 nM for EAAT1 and >300 μM for EAAT2-5. | ||
| M8800 | T3MG | Others |
| T3MG is a selective inhibitor of excitatory amino acid transporters GLT-1, EAAT2, and EAAT4. | ||
| M8850 | WAY-213613 | EAAT |
| Way-213613 is a potent, selective, non-substrate reuptake inhibitor of GLT-1/EAAT2 with an IC50 of 85 nM against EAAT2. The selectivity of WAY-213613 hydrochloride to EAAT1 and EAAT3 was 59 and 44 times higher (IC50 was 5 and 3.8 μM, respectively). Way-213613 has no activity on ionic and metabolic glutamate receptors. | ||
| M10023 | DL-TBOA | EAAT |
| DL-Threo-Beta-Benzyloxyaspartic acid | ||
| DL-TBOA is a potent non-transportable inhibitor of excitatory amino acid transporters with IC50s of 70 μM, 6 μM and 6 μM for excitatory amino acid transporter-1 (EAAT1), EAAT2 and EAAT3, respectively. | ||
| M14213 | WAY-213613 hydrochloride | EAAT |
| WAY-213613 hydrochloride is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC50 of 85 nM EAAT2. | ||
| M20510 | Chicago Sky Blue 6B | Others |
| A potent inhibitor of L-glutamate uptake via glutamate transporter (EAAT) | ||
| M30117 | GT 949 | EAAT |
| GT 949 is a selective excitatory amino acid transporter-2 (EAAT2) positive allosteric modulator with an EC50 of 0.26 nM. | ||
| M30150 | TFB-TBOA | EAAT |
| CF3-Bza-TBOA | ||
| TFB-TBOA (CF3-Bza-TBOA) is a potent glutamate transporter blocker that potently suppresses the activity of glial transporters. TFB-TBOA shows IC50 values of 22, 17, and 300 nM for glutamate transporters EAAT1, EAAT2, and EAAT3 respectively in an uptake assay using cells transiently expressing EAATs. | ||
| M40547 | Trigriluzole | EAAT |
| Troriluzole; BHV-4157 | ||
| Trigriluzole is an excitatory amino acid transporter protein 2 (EAAT2) modulator that increases the uptake of glutamate at neuronal synapses by increasing the expression and enhancing the function of EAAT in glial cells, thereby decreasing glutamate levels in neuronal synapses. It can be used in studies related to spinocerebellar ataxia (SCA) and anxiety disorders. | ||
| M40548 | Troriluzole Hydrochloride | EAAT |
| BHV-4157 hydrochloride; Trigriluzole hydrochloride | ||
| Troriluzole Hydrochloride is the hydrochloride form of Troriluzole, and is also an excitatory amino acid transporter protein 2 (EAAT2) modulator, which increases glutamate uptake at neuronal synapses by increasing the expression of EAAT in neuroglia and enhancing its function, thereby decreasing glutamate levels in neuronal synapses. It can be used in studies related to spinocerebellar ataxia (SCA) and anxiety disorders. | ||
| M56467 | L-threo-3-Hydroxyaspartic acid | EAAT |
| L-threo-3-Hydroxyaspartic acid is a potent EAAT inhibitor with Kis of 11, 19 and 14 μM for EAAT1, EAAT2 and EAAT3, respectively in HEK293 cell lines. | ||
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