About 7 results found for searched term "E 2012" (0.136 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2160 | Reboxetine mesylate | Adrenergic Receptor |
| FCE20124 mesylate; PNU155950E mesylate | ||
| Reboxetine mesylate is a potent and selective inhibitor of noradrenalin uptake (Ki values are 1.1, 129 and > 10000 nM for rat NET, SERT and DAT respectively). | ||
| M14583 | E 2012 | Gamma-secretase/Beta-secretase |
| E2012 | ||
| E 2012 is a potent gamma (γ) secretase modulator without affecting Notch processing. | ||
| M11367 | Filipin | Antibiotic |
| Filipin complex from Streptomyces filipinensis | ||
| Filipin is a 28-member cyclopentaene macrolide antifungal antibiotic produced by S. avermitilis and S. Miharaensis in 2012. Filipin can interact with phytosterol to change the membrane structure. Filipin III is the main component of Filipin. | ||
| M14432 | FASN-IN-4 tosylate | FAS |
| FASN-IN-4 tosylate is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 tosylate also inhibits SARS-CoV-2 with an EC50 of 18.6 nM. | ||
| M28236 | OTS447 | FLT3 |
| OTS447 is a potent FLT3 inhibitor with an IC50 of 21 nM (WO2012016082A1, compound 335). | ||
| M29580 | SYY-B085-1 | Histone Acetyltransferase |
| SYY-B085-1 is a histone acetyltransferase (HAT) inhibitor extracted from patent WO2019201291A1. | ||
| M49555 | JAK-IN-11 | JAK |
| JAK-IN-11 is a potent and selective JAK inhibitor extracted from patent WO2012122452A1, Compound II, has the potential for the skin disorders (such as cutaneous lupus) treatment. | ||
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