About 12 results found for searched term "Doxorubicin" (0.065 seconds)
Cat.No. | Name | Target |
---|---|---|
M1969 | Doxorubicin HCL | Animal Modeling |
RP 13057 hydrochloride; Adriamycin; Hydroxydaunorubicin hydrochloride; ADR; DOX | ||
Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. | ||
M5617 | Epirubicin hydrochloride | Topoisomerase |
4'-Epidoxorubicin hydrochloride; Epirubicin HCl | ||
Epirubicin hydrochloride, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Epirubicin hydrochloride inhibits DNA and RNA synthesis. Epirubicin hydrochloride is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity. | ||
M13746 | Aldoxorubicin | Topoisomerase |
INNO-206; DOXO-EMCH | ||
Aldoxorubicin (INNO-206) is an albumin-binding prodrug of Doxorubicin (DNA topoisomerase II inhibitor), which is released from albumin under acidic conditions. | ||
M22220 | Doxorubicinone | Others |
Doxorubicinone | ||
M27770 | Nemorubicin | DNA/RNA Synthesis |
Methoxymorpholinyl doxorubicin; FCE 23762; PNU 152243 | ||
Nemorubicin (Methoxymorpholinyl doxorubicin) is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair (NER) system to exert its activity. | ||
M28553 | MC-DOXHZN | Topoisomerase |
(E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone | ||
MC-DOXHZN ((E/Z)-Aldoxorubicin) is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties. | ||
M29508 | Doxorubicin | Topoisomerase |
Hydroxydaunorubicin | ||
Doxorubicin (Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication. Doxorubicin inhibits human DNA topoisomerase I with an IC50 of 0.8 μM. | ||
M30152 | MC-DOXHZN hydrochloride | Topoisomerase |
(E/Z)-Aldoxorubicin hydrochloride; Doxorubicin(6-maleimidocaproyl)hydrazone hydrochloride | ||
MC-DOXHZN ((E/Z)-Aldoxorubicin) hydrochloride is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties. | ||
M41610 | Aldoxorubicin hydrochloride | Topoisomerase |
Aldoxorubicin (INNO-206) hydrochloride is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), which is released from albumin under acidic conditions. | ||
M42355 | Doxorubicinol | Metabolite/Endogenous Metabolite |
Doxorubicinol, a potent inhibitor of the cardiac sarcoplasmic reticulum calcium pump, inhibits systolic myocardial function in isolated heart muscle. | ||
M53151 | Zoptarelin doxorubicin | LHRH/GnRH |
Zoptarelin doxorubicin (AEZS-108; AN-152) is a hybrid anticancer agent, containing Zoptarelin and Doxorubicin. | ||
M55735 | Doxorubicin-SMCC | Drug-Linker Conjugates for ADC |
Doxorubicin-SMCC is a agent-linker conjugate for ADC. |
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