About 12 results found for searched term "Doxorubicin" (0.11 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1969 | Doxorubicin HCL | Animal Modeling |
| RP 13057 hydrochloride; Adriamycin; Hydroxydaunorubicin hydrochloride; ADR; DOX | ||
| Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. | ||
| M5617 | Epirubicin hydrochloride | Topoisomerase |
| 4'-Epidoxorubicin hydrochloride; Epirubicin HCl | ||
| Epirubicin hydrochloride, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Epirubicin hydrochloride inhibits DNA and RNA synthesis. Epirubicin hydrochloride is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity. | ||
| M13746 | Aldoxorubicin | Topoisomerase |
| INNO-206; DOXO-EMCH | ||
| Aldoxorubicin (INNO-206) is an albumin-binding prodrug of Doxorubicin (DNA topoisomerase II inhibitor), which is released from albumin under acidic conditions. | ||
| M22220 | Doxorubicinone | Metabolite/Endogenous Metabolite |
| Adriamycin aglycone; Adriamycinone | ||
| Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. | ||
| M27770 | Nemorubicin | DNA/RNA Synthesis |
| Methoxymorpholinyl doxorubicin; FCE 23762; PNU 152243 | ||
| Nemorubicin (Methoxymorpholinyl doxorubicin) is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair (NER) system to exert its activity. | ||
| M28553 | MC-DOXHZN | Topoisomerase |
| (E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone | ||
| MC-DOXHZN ((E/Z)-Aldoxorubicin) is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties. | ||
| M29508 | Doxorubicin | Topoisomerase |
| Hydroxydaunorubicin | ||
| Doxorubicin (Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication. Doxorubicin inhibits human DNA topoisomerase I with an IC50 of 0.8 μM. | ||
| M30152 | MC-DOXHZN hydrochloride | Topoisomerase |
| (E/Z)-Aldoxorubicin hydrochloride; Doxorubicin(6-maleimidocaproyl)hydrazone hydrochloride | ||
| MC-DOXHZN ((E/Z)-Aldoxorubicin) hydrochloride is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties. | ||
| M41610 | Aldoxorubicin hydrochloride | Topoisomerase |
| Aldoxorubicin (INNO-206) hydrochloride is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), which is released from albumin under acidic conditions. | ||
| M42355 | Doxorubicinol | Metabolite/Endogenous Metabolite |
| Doxorubicinol, a potent inhibitor of the cardiac sarcoplasmic reticulum calcium pump, inhibits systolic myocardial function in isolated heart muscle. | ||
| M53151 | Zoptarelin doxorubicin | LHRH/GnRH |
| Zoptarelin doxorubicin (AEZS-108; AN-152) is a hybrid anticancer agent, containing Zoptarelin and Doxorubicin. | ||
| M55735 | Doxorubicin-SMCC | Drug-Linker Conjugates for ADC |
| Doxorubicin-SMCC is a agent-linker conjugate for ADC. | ||
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