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Aldoxorubicin

Cat. No. M13746

All AbMole products are for research use only, cannot be used for human consumption.

Aldoxorubicin Structure
Synonym:

INNO-206; DOXO-EMCH

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Quality Control & Documentation
Biological Activity

Aldoxorubicin (INNO-206) is an albumin-binding prodrug of Doxorubicin (DNA topoisomerase II inhibitor), which is released from albumin under acidic conditions. Aldoxorubicin (INNO-206) has potent antitumor activities in various cancer cell lines and in murine tumor models.

<span style='color:#ff0000;'><strong>*The compound is unstable in solutions, freshly prepared is recommended</strong></span>


Chemical Information
Molecular Weight 750.75
CAS Number 1361644-26-9
Solubility (25°C) DMSO 55 mg/mL
Storage -20°C, sealed
References

[1] Lee D Cranmer. Onco Targets Ther. Spotlight on aldoxorubicin (INNO-206) and its potential in the treatment of soft tissue sarcomas: evidence to date

[2] Florence E Chamberlain, et al. Future Oncol. Aldoxorubicin in soft tissue sarcomas

[3] Mahesh Seetharam, et al. Future Oncol. Aldoxorubicin therapy for the treatment of patients with advanced soft tissue sarcoma

[4] Jun Gong, et al. Drug Des Devel Ther. Aldoxorubicin: a tumor-targeted doxorubicin conjugate for relapsed or refractory soft tissue sarcomas

[5] Esha Sachdev, et al. Expert Opin Investig Drugs. Aldoxorubicin for the treatment of soft tissue sarcoma

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  Catalog
Abmole Inhibitor Catalog




Keywords: Aldoxorubicin, INNO-206; DOXO-EMCH supplier, Topoisomerase, inhibitors, activators

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