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 About 7 results found for searched term "DNMT-IN-3" (0.13 seconds)

Cat.No.  Name Target
M41211 DNMT-IN-3 Parasite
DNMT-IN-3 is an DNA Methyltransferase (DNMT) inhibitor, and plays an antimalarial role with IC50 of 60 nM against Plasmodium falciparum (Plasmodium).
M3008 SGI-1027 DNA Methyltransferase
DNA Methyltransferase Inhibitor II
SGI-1027 is a DNMT inhibitor with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B
M10985 γ-Oryzanol DNA Methyltransferase
γ-Oryzanol effectively inhibits DNA methyltransferases (DNMTs) in mouse striatum. Suppression of DNMT1 and DNMT3a,IC50 3.2 μM and 22.3 μM, respectively.
M13815 GSK-3484862 DNA Methyltransferase
GSK-3484862 is a non-covalent inhibitor for Dnmt1. GSK-3484862 induces DNA hypomethylation to against cancer. GSK-3484862 mediates global demethylation in murine embryonic stem cells.
M41639 DNMT-IN-1 DNA Methyltransferase
DNMT-IN-1 is a potent DNMT inhibitor with an EC50 value of 3.2 µM.
M45092 (R)-GSK-3685032 DNA Methyltransferase
(R)-GSK-3685032 is the R-isomer of GSK-3685032.GSK-3685032 is a non-time-dependent, non-covalent, first-in-class, reversible selective inhibitor of DNMT1 with an IC50 value of 0.036 μM.GSK-3685032 induces DNA GSK-3685032 induces loss of DNA methylation, transcriptional activation and cancer cell growth inhibition.
M45093 (S)-GSK-3685032 DNA Methyltransferase
(S)-GSK-3685032 is the inactive isomer of GSK-3685032.GSK-3685032 is a non-time-dependent, non-covalent, first-in-class, reversible selective inhibitor of DNMT1 with an IC50 value of 0.036 μM.GSK-3685032 induces DNA GSK-3685032 induces loss of DNA methylation, transcriptional activation and cancer cell growth inhibition.



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