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(S)-GSK-3685032

Cat. No. M45093

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(S)-GSK-3685032 Structure
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Biological Activity

(S)-GSK-3685032 is the inactive isomer of GSK-3685032.GSK-3685032 is a non-time-dependent, non-covalent, first-in-class, reversible selective inhibitor of DNMT1 with an IC50 value of 0.036 μM.GSK-3685032 induces DNA GSK-3685032 induces loss of DNA methylation, transcriptional activation and cancer cell growth inhibition.

Chemical Information
Molecular Weight 420.53
Formula C22H24N6OS
CAS Number 2170142-58-0
Form Solid
Storage 4°C, protect from light, dry, sealed
References

[1] Nathalia Azevedo Portilho, et al. Epigenetics Chromatin. The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells

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(R)-GSK-3685032

(R)-GSK-3685032 is the R-isomer of GSK-3685032.GSK-3685032 is a non-time-dependent, non-covalent, first-in-class, reversible selective inhibitor of DNMT1 with an IC50 value of 0.036 μM.GSK-3685032 induces DNA GSK-3685032 induces loss of DNA methylation, transcriptional activation and cancer cell growth inhibition.

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  Catalog
Abmole Inhibitor Catalog




Keywords: (S)-GSK-3685032 supplier, DNA Methyltransferase, inhibitors, activators

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