About 30 results found for searched term "DAB" (0.043 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1674 | BIBR 953 | Thrombopoietin/Thrombin |
| Dabigatran, Pradaxa; BIBR 953ZW | ||
| BIBR 953 (Dabigatran, Pradaxa) is an oral anticoagulant from the class of the direct thrombin inhibitors. | ||
| M1855 | Dabrafenib Mesylate | Raf |
| GSK-2118436B | ||
| Dabrafenib (GSK2118436) is a selective, orally bioavailable inhibitor of Mutant B-raf (BRAF) protein kinase with potential antineoplastic activity. | ||
| M1988 | Dabrafenib | Raf |
| GSK2118436 | ||
| Dabrafenib (free base) (GSK2118436A) is a V600 mutant BRAF-specific inhibitor. | ||
| M3574 | Dabigatran Etexilate | Thrombopoietin/Thrombin |
| BIBR-1048 | ||
| Dabigatran Etexilate is the procompound of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule. | ||
| M3759 | Dabigatran etexilate mesylate | Thrombopoietin/Thrombin |
| BIBR 1048MS | ||
| Dabigatran etexilate mesylate is a direct thrombin inhibitor. | ||
| M3978 | 10-Deacetylbaccatin III | Others |
| 10-DAB III | ||
| 10-Deacetylbaccatin-III is an intermediate for taxol analog preparations. | ||
| M14538 | Dabigatran (ethyl ester) | Thrombopoietin/Thrombin |
| Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. | ||
| M14539 | Dabigatran ethyl ester hydrochloride | Thrombopoietin/Thrombin |
| Dabigatran ethyl ester hydrochloride is a potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and a thrombin inhibitor. | ||
| M20865 | L-DAB HBR | GABA Receptor |
| L-DABA, L-2,4-Diaminobutyric acid | ||
| L-DAB HBR (L-Dab Hydrobromide, L-2,4-Diaminobutyric acid hydrobromide) is an inhibitor of GABA (Gamma-aminobutyric acid) transaminase with IC50 of >500 μM. L-DAB HBR exhibits antitumor activity. | ||
| M21174 | Ledaborbactam etzadroxil | Others |
| VNRX-7145 | ||
| Serine_lactamase inhibitor VNRX-7145 is an oral biologic formulation of the boronic acid-containing inhibitor VNRX-5236, currently in Phase I. | ||
| M24791 | Denileukin diftitox | IL Receptor/Related |
| DAB 389IL-2; E7777; LY335348 | ||
| Denileukin diftitox (DAB 389IL-2) is a diphtheria toxin (DT)-related interleukin 2 (IL-2) fusion protein toxin that depletes cells expressing the high-affinity form of the IL-2 receptor (IL-2R), CD25. Denileukin diftitox binds to cells expressing IL-2R and inhibits protein synthesis through internalization of the diphtheria toxin fragment. | ||
| M24895 | Melredableukin alfa | IL Receptor/Related |
| RG7835; RO7049665 | ||
| Melredableukin alfa (RO-7049665) is a fusion protein that consists of a human IgG1-κ fused to a mutated human interleukin 2 (IL2 mutein) via a peptide linker. Melredableukin alfa can be used for the research of autoimmune hepatitis and ulcerative colitis. | ||
| M25368 | Vixtimotamab | Aminopeptidase |
| AMV-564; TandAb T564 | ||
| Vixtimotamab (AMV-564; TandAb T564) is a bispecific tetravalent tandem diabody (TandAb) that targets human CD33 and human CD3 antigens. Vixtimotamab can be used for the research of acute myeloid leukemia (AML). | ||
| M27613 | Irdabisant hydrochloride | Histamine Receptor |
| CEP-26401 hydrochloride | ||
| Irdabisant (CEP-26401) hydrochloride is a selective, orally active and blood-brain barrier (BBB) penetrant histamine H3 receptor (H3R) inverse agonist/inverse agonist with Ki values of 7.2 nM and 2.0 nM for rat H3R and human H3R, respectively. Irdabisant hydrochloride has relatively low inhibitory activity against hERG current with an IC50 of 13.8 μM. | ||
| M27614 | Irdabisant | Histamine Receptor |
| CEP-26401 | ||
| Irdabisant (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant histamine H3 receptor (H3R) inverse agonist/inverse agonist with Ki values of 7.2 nM and 2.0 nM for rat H3R and human H3R, respectively. Irdabisant has relatively low inhibitory activity against hERG current with an IC50 of 13.8 μM. Irdabisant has cognition-enhancing and wake-promoting activities in the rat social recognition model. Irdabisant can be used to research schizophrenia or cognitive impairment. | ||
| M27733 | Lei-Dab7 | Potassium Channel |
| Lei-Dab7 is a potent and selective SK2 (KCa2.2) channels blocker with a Kd of 3.8 nM. Lei-Dab7 shows low or no activity on KCa1, KCa3, Kv and Kir2.1 channels. | ||
| M31051 | Lei-Dab7 TFA | Potassium Channel |
| Lei-Dab7 TFA is a high affinity, selective KCa2.2 (SK2) channel blocker (Kd=3.8 nM). Lei-Dab7 TFA exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, Kv and Kir2.1. | ||
| M38798 | Pyridaben | Parasite |
| Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function. | ||
| M43235 | Dabcyl-LNKRLLHETQ-Edans | Others |
| Dabcyl-LNKRLLHETQ-Edans (Fluorigenic PEXEL peptide) is a biological active peptide. | ||
| M43276 | Dabcyl-AGHDAHASET-Edans | Others |
| Dabcyl-AGHDAHASET-Edans is a biological active peptide. | ||
| M43280 | Dabcyl-QALPETGEE-Edans | Others |
| Dabcyl-QALPETGEE-Edans is a biological active peptide. | ||
| M43290 | DABCYL-LPETG-EDANS | Others |
| DABCYL-LPETG-EDANS is a biological active peptide. | ||
| M49811 | Dimethyldioctadecylammonium bromide | Liposome |
| Dioctadecyldimethylammonium bromide; DODAB; DDAB | ||
| Dimethyldioctadecylammonium bromide is a synthetic cationic lipid consisting of a positively charged ammonium head group and two long hydrophobic tails that can be used to form liposomes and other lipid-based nanoparticles, which are commonly used in studies related to gene delivery and vaccine development. | ||
| M51011 | DABCYL-VNLDAE-EDANS | Others |
| DABCYL-VNLDAE-EDANS is a substrate of b-secretase. | ||
| M51099 | DABCYL-SEVNLDAEF-EDANS | Others |
| DABCYL-SEVNLDAEF-EDANS is a substrate of FRET. | ||
| M51316 | DABCYL-TNF-α-EDANS (-4 to +6) (human) | Others |
| DABCYL-TNF-α-EDANS (-4 to +6) (human) is a FRET peptide substrate of tumor necrosis factor convertase (TACE). | ||
| M51361 | DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS | Others |
| DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is a biological active peptide. | ||
| M51387 | Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 | Others |
| Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 (HCV NS3 protease substrate) is a biological active peptide. | ||
| M51604 | Dabcyl-RGVVNASSRLA-Edans | Others |
| Dabcyl-RGVVNASSRLA-Edans (Dabcyl-CMV-Edans) is a fluorogenic substrate for human cytomegalovirus (HCMV) protease. | ||
| M51650 | Glu(EDANS)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(DABCYL) | Others |
| Glu(EDANS)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(DABCYL) is a calpain substrate. | ||
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