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Denileukin diftitox (DAB 389IL-2) is a diphtheria toxin (DT)-related interleukin 2 (IL-2) fusion protein toxin that depletes cells expressing the high-affinity form of the IL-2 receptor (IL-2R), CD25. Denileukin diftitox binds to cells expressing IL-2R and inhibits protein synthesis through internalization of the diphtheria toxin fragment.
| CAS Number | 173146-27-5 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] No authors listed. Denileukin Diftitox
[2] No authors listed. Denileukin Diftitox
[3] George Manoukian, et al. Expert Opin Biol Ther. Denileukin diftitox: a novel immunotoxin
[4] John W Eklund, et al. Expert Rev Anticancer Ther. Denileukin diftitox: a concise clinical review
[5] D P Figgitt, et al. Am J Clin Dermatol. Denileukin diftitox
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