About 30 results found for searched term "Chalcone" (0.026 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4009 | Licochalcone-B | Caspase |
| Licochalcone A is a chalconoid, a type of natural phenols. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata. | ||
| M4012 | Licochalcone-A | Autophagy |
| Licochalcone-A; Lico A | ||
| Licochalcone A is an estrogenic flavonoid derived from licorice that induces Nrf2-mediated defense mechanisms and ameliorates acetaminophen and endotoxin-induced liver injury. In addition, Licochalcone A has antimalarial, anticancer, antibacterial and antiviral activities. | ||
| M4014 | Licochalcone-C | Glucosidase |
| Lico-C | ||
| Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. Licochalcone-C is an inhibitor of lipopolysaccharide-interferon-γ inflammation. | ||
| M4844 | Isobavachalcone | Autophagy |
| Corylifolinin; Isobacachalcone | ||
| Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma. | ||
| M5301 | (E)-Cardamonin | NLR |
| Alpinetin chalcone | ||
| (E)-Cardamonin is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM, Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway. | ||
| M7630 | Butein | PDE |
| 2’,3,4,4’-tetrahydroxy Chalcone | ||
| Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4. Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a. Butein is a SIRT1 activator. | ||
| M9645 | Licochalcone D | NF-κB |
| Licochalcone D is a potent inhibitor of NF-kappaB (NF-κB) p65 with antioxidant, anti-inflammatory, anti-cancer properties. | ||
| M13460 | Bavachalcone | Antibiotic |
| Broussochalcone B | ||
| Bavachalcone is a major bioactive compounds isolated from Psoralea corylifolia L.; has been widely used as traditional Chinese medicine; antibiotic or anticancer agent. | ||
| M14102 | Cardamonin | NLR |
| Cardamomin; Alpinetin chalcone | ||
| Cardamonin (Cardamomin) acts as an aryl hydrocarbon receptor (AhR) activator. Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway. | ||
| M16216 | 2',4',6'-Trihydroxydihydrochalcone 4'-O-glucoside | Chalcones |
| 2',4',6'-Trihydroxydihydrochalcone 4'-O-glucoside | ||
| M16217 | 2'-Hydroxy-3',4',6'-trimethoxydihydrochalcone | Chalcones |
| 2'-Hydroxy-3',4',6'-trimethoxydihydrochalcone | ||
| M16218 | 2',4'-Dihydroxy-3',6'-dimethoxychalcone | Chalcones |
| 2',4'-Dihydroxy-3',6'-dimethoxychalcone | ||
| M16219 | 2'-Hydroxy-3',4',6'-trimethoxychalcone | Chalcones |
| 2'-Hydroxy-3',4',6'-trimethoxychalcone | ||
| M16220 | 2-Hydroxy-3,4,5,6-tetramethoxychalcone | Chalcones |
| 2-Hydroxy-3,4,5,6-tetramethoxychalcone | ||
| M16221 | 2',4',6'-Trihydroxydihydrochalcone | Chalcones |
| 2',4',6'-Trihydroxydihydrochalcone | ||
| M16223 | 4,2'-Dihydroxy-4'-methoxychalcone | Chalcones |
| 4,2'-Dihydroxy-4'-methoxychalcone | ||
| M16224 | 4'-Hydroxy-2,4-dimethoxychalcone | Chalcones |
| 4'-Hydroxy-2,4-dimethoxychalcone | ||
| M16225 | Tetrahydroxymethoxychalcone | Chalcones |
| Tetrahydroxymethoxychalcone | ||
| M16228 | Cyclobutanedichalcone | Chalcones |
| Cyclobutanedichalcone | ||
| M16229 | Pinostrobin chalcone | Chalcones |
| Pinostrobin chalcone | ||
| M16230 | Pinocembrin chalcone | Chalcones |
| Pinocembrin chalcone | ||
| M17992 | 4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone | COX |
| 4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone | ||
| M18255 | Hesperidin methylchalcone | NF-κB |
| Hesperidin methylchalcone is an orally active flavonoid that has analgesic, anti-inflammatory and antioxidant properties. Hesperidin methylchalcone exhibits vasoprotective activity. Hesperidin methylchalcone inhibits oxidative stress, cytokine production and NF-κB activation. | ||
| M18294 | 4'-O-Methylbavachalcone | Others |
| 4'-O-Methylbavachalcone | ||
| M18431 | Naringenin chalcone | Others |
| Naringenin chalcone | ||
| M18758 | Licochalcone E | Others |
| Licochalcone E | ||
| M20429 | 4-Hydroxychalcone | Others |
| P-Cinnamoylphenol | ||
| 4-Hydroxychalcone is a chalcone metabolite with diverse biological activities. It inhibits TNFα-induced NF-κB pathway activation in a dose-dependent manner and also activates BMP signaling. | ||
| M20439 | 4'-Hydroxychalcone | Others |
| P-Cinnamoylphenol | ||
| 4'-Hydroxychalcone, found in herbs and spices and tea, is a member of the class of compounds known as retrochalcones. It has diverse biological activities, inhibiting TNFα-induced NF-κB pathway activation in a dose-dependent manner and activating BMP signaling. | ||
| M21045 | 4'-Methoxychalcone | Others |
| 4'-Methoxychalcone, found in citrus, is chalcone derivative that has shown diverse pharmacological properties, including anti-tumor and anti-inflammatory activities. | ||
| M27815 | 3-Deoxysappanchalcone | Anti-infection |
| 3-Deoxysappanchalcone is a naturally-occurring chalcone compound isolated from Caesalpinia sappan L. (Leguminosae), which possesses anti-allergic, antiviral, anti-inflammatory and antioxidant activities. 3-Deoxysappanchalcone exerts anti-inflammatory activity via induce heme oxygenase-1 (HO-1) expression by activating the AKT/mTOR pathway in murine macrophages. 3-Deoxysappanchalcone also exhibits anti-influenza virus activity (H3N2, IC50 = 1.06 μM). | ||
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