About 7 results found for searched term "BAI1" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M13529 | BAI1 | Bcl-2 |
| BAI1 is a selective and allosteric inhibitor of BAX, an apoptosis regulator. BAI1 directly binds to BAX and allosterically inhibits BAX activation. BAI1 has the potential for the research of diseases mediated by BAX-dependent cell death. | ||
| M2904 | Ouabain | ATPase |
| Ouabain is a selective Na+/K+, -ATPase inhibitor, binds to α2 /α3 subunit with Ki of 41 nM/15 nM. | ||
| M3938 | Baicalin | GABA Receptor |
| Baicalein 7-O-β-D-glucuronide; 5, 6-dihydroxy-7-O-glucuronide flavone | ||
| Baicalin is an allosteric carnitine palmityl transferase 1 (CPT1) activator. Baicalin reduces the expression of NF-κB. | ||
| M3970 | Scutellarin | STAT |
| Scutellarin, an active flavone isolated from Scutellaria baicalensis, is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC50s of 26 μM, 253 μM and 136 μM, respectively. Scutellarin inhibited caspase-11 activation and pyroptosis in macrophages at least partly via regulating the PKA signaling pathway. | ||
| M6098 | Baicalein | Others |
| 5,6,7-Trihydroxyflavone | ||
| Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. | ||
| M29899 | KCC-07 | DNA Alkylator/Crosslinker |
| KCC-07 is a potent, selective and brain-penetrant MBD2 (methyl-CpG-binding domain protein 2) inhibitor. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. Anticancer activity. | ||
| M38942 | Dihydrobaicalein | PLK |
| Dihydrobaicalein is a PLK1 Inhibitor with an IC50 of 6.3 μM. Dihydrobaicalein also inhibits VRK2 and PLK2. Dihydrobaicalein is a natural product that can be isolated from Scutellaria scandens. | ||
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