Free shipping on all orders over $ 500

BAI1

Cat. No. M13529

All AbMole products are for research use only, cannot be used for human consumption.

BAI1 Structure
Size Price Availability Quantity
5mg USD 95  USD95 In stock
10mg USD 150  USD150 In stock
25mg USD 300  USD300 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

BAI1 is a selective and allosteric inhibitor of BAX, an apoptosis regulator. BAI1 directly binds to BAX and allosterically inhibits BAX activation. BAI1 has the potential for the research of diseases mediated by BAX-dependent cell death.

Chemical Information
Molecular Weight 467.2
CAS Number 335165-68-9
Solubility (25°C) DMSO 18.67 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Martin Pesta, et al. Anticancer Res. BAI1 as a Prognostic Marker of Clear Cell Renal Cell Carcinoma (ccRCC)

[2] Hyo Jung An, et al. Thorac Cancer. BAI1 nuclear expression reflects the survival of nonsmoking non-small cell lung cancer patients

[3] Lei Liu, et al. Carcinogenesis. BAI1 acts as a tumor suppressor in lung cancer A549 cells by inducing metabolic reprogramming via the SCD1/HMGCR module

[4] Jinghua Cao, et al. Angiogenesis. Decylubiquinone suppresses breast cancer growth and metastasis by inhibiting angiogenesis via the ROS/p53/ BAI1 signaling pathway

[5] Joseph G Duman, et al. Elife. The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest

Related Bcl-2 Products
ABBV-467 

ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM).

WEHI-539 

WEHI-539 is a selective inhibitor of Bcl-XL with an IC50 of 1.1 nM.

(Rac)-Lisaftoclax

(Rac)-Lisaftoclax ((Rac)-APG-2575) is a Bcl-2 inhibitor that can be uesd for hematologic malignancy research.

BcI-2/BcI-xI ligand 1 

BcI-2/BcI-xI ligand 1 is a BcI-2/BcI-xI ligand, and can be used for synthesis of PROTAC BcI-2/BcI-xI Degrader-1.

AZD-5991 (S-enantiomer) 

AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991.

  Catalog
Abmole Inhibitor Catalog




Keywords: BAI1 supplier, Bcl-2, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.