About 6 results found for searched term "Apelin-13" (0.133 seconds)
Cat.No. | Name | Target |
---|---|---|
M10097 | Apelin-13 TFA | Apelin Receptor |
Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC 50 value of 0.37 nM. | ||
M10197 | (Glp1)-Apelin-13 human, bovine | Apelin Receptor |
[Pyr1]-Apelin-13 | ||
(Glp1)-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist. | ||
M20849 | (Ala13)-Apelin-13 | Others |
(Ala13)-Apelin-13 is a potent APJ receptor antagonist and can prevent the apelin-induced reduction in gastric tone and motility. | ||
M53258 | Apelin-13 | Apelin Receptor |
Apelin-13 is an endogenous ligand for the G-protein coupled receptor angiotensin II protein J (APJ), activating this G protein-coupled receptor with an EC 50 value of 0.37 nM. | ||
M6972 | ML221 | Apelin Receptor |
ML-221 | ||
ML221 is an Apelin (APJ) antagonist and inhibits apelin-13-mediated activation of APJ. IC50 values of cAMP and β -Arrestin were 0.70 μM and 1.75 μM, respectively. EC80 values were all 10 nM. | ||
M29139 | BMS-986224 | Others |
BMS-986224 is a potent, selective and orally active APJ receptor agonist (Kd = 0.3 nM). BMS-986224 exhibits similar receptor binding and signaling profile to (Pyr1) apelin-13. BMS-986224 has the potential for the research of heart failure. |
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