About 15 results found for searched term "AR-42" (0.055 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1661 | AZD6244 | MEK |
| Selumetinib, ARRY-142886 | ||
| AZD6244 (ARRY-142886, Selumetinib) is a potent MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nM. | ||
| M1662 | AZD8330 | MEK |
| ARRY-424704, ARRY-704 | ||
| AZD8330 (ARRY-424704) is a novel, selective, highly efficacious, uncompetitive MEK inhibitor with an IC50 of 7 nM. | ||
| M2468 | Brimonidine Tartrate | Adrenergic Receptor |
| Brimonidine tartrate; AGN190342 tartrate; UK14304 tartrate | ||
| Brimonidine Tartrate is a highly selective α-adrenergic receptor antagonist with an EC50 of 0.45 nM for α2A adrenoreceptor, and has been used to study open-angle glaucoma or ocular hypertension. | ||
| M3405 | AR-42 | HDAC |
| HDAC-42 | ||
| AR-42 is an HDAC inhibitor with IC50 of 30 nM. | ||
| M3440 | Nilvadipine | Calcium Channel |
| ARC029, FR34235 | ||
| Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM. | ||
| M4879 | Cycloheximide | DNA/RNA Synthesis |
| Naramycin A; Actidione; CHX; FT 3422-2; NM-MCD 80 | ||
| Cycloheximide is an inhibitor of protein biosynthesis in eukaryotic organisms, with IC50 of 532.5 nM. | ||
| M6182 | 7ACC1 | Monocarboxylate Transporter (MCT) |
| DEAC; Coumarin D 1421; D 1421 | ||
| 7ACC1(DEAC; Coumarin D 1421; D 1421) selectively interfere with lactate fluxes in the lactate-rich tumor microenvironment; inhibits lactate influx but not efflux in tumor cells expressing MCT1 and MCT4 transporters. | ||
| M6454 | AR420626 | GPR/FFAR |
| AR-420626 | ||
| AR420626 is a selective agonist of free fatty acid receptor 3 (FFAR3, GPR41) with IC50 of 117 nM. | ||
| M10274 | Tolebrutinib | BTK |
| SAR442168; PRN2246 | ||
| Tolebrutinib (SAR442168) is a potent, selective, orally active and blood-brain barrier capable bruton's tyrosine kinase (BTK) inhibitor with IC50 values of 0.4 and 0.7 nM in Ramos B cells and HMC microglia, respectively. Tolebrutinib has an effect on central nervous system immunity. Tolebrutinib can be used in multiple sclerosis (MS) studies. | ||
| M14171 | Selumetinib sulfate | MEK |
| AZD6244 sulfate; ARRY-142886 sulfate | ||
| Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation. | ||
| M45149 | Vari Fluor 425 SE | Fluorescent Dye |
| VF 425 SE | ||
| Vari Fluor 425 SE is a Vari Fluor SE series labeling dye (Ex/Em=430 nm/475 nm).The Vari Fluor SE series dyes are a class of fluorescent dyes that contain NHS ester groups for labeling antibodies, proteins, peptides, amine-modified oligonucleotides, and free amines (-NHX) on other biomolecules. | ||
| M49407 | Fipaxalparant | LPL Receptor |
| SAR-100842; HZN-825 | ||
| Fipaxalparant is a potent, orally active and selective LPA1 receptor antagonist for studies related to idiopathic pulmonary fibrosis (IPF). | ||
| M52474 | Cys-Gly-Lys-Arg-Amyloid β-Protein (1-42) | Amyloid |
| Cys-Gly-Lys-Arg-Amyloid β-Protein (1-42) is a peptide fragment of amyloid β-protein (Aβ). | ||
| M53534 | Epstein-barr virus BRLF1 (134-142) | Anti-infection |
| Epstein-barr virus BRLF1 (134-142) is a biological active peptide. | ||
| M54591 | SAR-442501 | FGFR |
| SAR-442501 is a novel anti-FGFR3 monoclonal antibody for studies related to achondroplasia (ACH). | ||
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