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Selumetinib sulfate

Cat. No. M14171

All AbMole products are for research use only, cannot be used for human consumption.

Selumetinib sulfate Structure
Synonym:

AZD6244 sulfate; ARRY-142886 sulfate

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Quality Control & Documentation
Biological Activity

Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.

Chemical Information
Molecular Weight 555.76
CAS Number 943332-08-9
Storage 2-8°C, dry, sealed
References

[1] Evgeny N Imyanitov, et al. Treating non-small cell lung cancer with selumetinib: an up-to-date drug evaluation

[2] Giulio Metro, et al. Selumetinib: a promising pharmacologic approach for KRAS-mutant advanced non-small-cell lung cancer

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  Catalog
Abmole Inhibitor Catalog




Keywords: Selumetinib sulfate, AZD6244 sulfate; ARRY-142886 sulfate supplier, MEK, inhibitors, activators

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