About 5 results found for searched term "AL-611" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21285 | AL-611 | HCV Protease |
| AL-611 is an HCV NS5B polymerase inhibitor (EC50 = 5 nM). | ||
| M5309 | ALK-IN-1 | ALK |
| ALK-IN-1 is an analog of AP26113 which is a potent and selective ALK inhibitor. It is also an inhibitor of EGFR. | ||
| M11405 | Inavolisib (GDC-0077) | PI3K |
| GDC-0077; RG6114；RO-7113755 | ||
| Inavolisib (GDC-0077; RG6114) is a potential best-in-class, orally selective PI3Kα inhibitor (IC50=0.038 nM). GDC-0077 (RG6114) exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. GDC-0077 (RG6114) is more selective for mutants compared to wild-type PI3Kα. It can trigger the degradation of mutation-producing PIK3α. | ||
| M21471 | Recombinant Human Transferrin (HEK293, C-6His) | Cytokines and Growth Factors |
| Serotransferrin; Transferrin; Beta-1 metal-binding globulin | ||
| Recombinant human transferrin is produced by mammalian expression system, and the target gene is encoded as Val20-Pro698, which is expressed by 6His marker at the C-terminal. Protein number: AAA61140.1. | ||
| M28672 | BMS-986118 | GPR/FFAR |
| BMS-986118 is a potent, orally active, and selective GPR40 agonist with an EC50 of 0.07 µM. BMS-986118 has dual insulinotropic and GLP-1 secretory effects, resulting in robust plasma glucose lowering effects in acute animal models. | ||
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