Free shipping on all orders over $ 500

BMS-986118 

Cat. No. M28672

All AbMole products are for research use only, cannot be used for human consumption.

BMS-986118  Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

BMS-986118 is a potent, orally active, and selective GPR40 agonist with an EC50 of 0.07 µM. BMS-986118 has dual insulinotropic and GLP-1 secretory effects, resulting in robust plasma glucose lowering effects in acute animal models.

Chemical Information
Molecular Weight 540.96
Formula C25H28ClF3N4O4
CAS Number 1610562-74-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Jun Shi, et al. J Med Chem. Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 Agonists

[2] Zheng Li, et al. Expert Opin Investig Drugs. Free fatty acid receptor agonists for the treatment of type 2 diabetes: drugs in preclinical to phase II clinical development

Related GPR/FFAR Products
GPR84 antagonist 8 

GPR84 antagonist 8 is a selective GPR84 antagonist.

ML191

ML-191 is an antagonist of GPR55.

CID1172084 

CID1172084 is a selective GPR55 agonist (EC50=0.16 μM).

ML 145 

ML 145 is a selective and competitive human GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM.

PSN 375963 hydrochloride 

PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: BMS-986118  supplier, GPR/FFAR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.