About 6 results found for searched term "AICAR" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4897 | AICAR | AMPK |
| Acadesine; AICA Riboside | ||
| AICAR is an adenosine analog and activator of AMPK that regulates glucose and lipid metabolism and inhibits the production of pro-inflammatory cytokines and iNOS. In addition, AICAR is an inhibitor of autophagy, YAP and mitophagy. | ||
| M13806 | AICAR phosphate | AMPK |
| Acadesine phosphate; AICA Riboside phosphate | ||
| AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. | ||
| M7108 | Pemetrexed | Antifolate |
| LY231514 | ||
| Pemetrexed is a thymidylate synthetase inhibitor, also inhibits dihydrofolate reductase, GARFT and AICART. | ||
| M10948 | MOTS-c(Human) Acetate | AMPK |
| MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate induces glucose uptake and improves insulin sensitivity. | ||
| M29037 | LSN 3213128 | Antifolate |
| LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity. | ||
| M51420 | N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine | Others |
| N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine has the function of interfering with PAICS protein, which can effectively reduce SAICAR and SAICAr accumulation. | ||
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