About 4 results found for searched term "AG 555" (0.133 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20583 | AG 555 | EGFR/HER2 |
| Tyrphostin B46 | ||
| AG-555 is an inhibitor of tyrosine kinase , interacts directly with topoisomerase I, thus preventing DNA relaxation. It inhibits EGFR with an IC50 of 0.7 μM. | ||
| M6887 | L755507 | Adrenergic Receptor |
| L-755,507 | ||
| L755507 is a potent, selective agonist of β3-AR with an IC50 of 35 nM. L755507 enhances the homology-directed repair (HDR)-mediated genome editing in CRISPR/Cas9 nickase system. | ||
| M10047 | Dorzagliatin | Glucokinase (GK) |
| HMS5552; RO5305552; Sinogliatin | ||
| Dorzagliatin (HMS-5552, RO-5305552, Sinogliatin) is a glucokinase (GK) activator, which improves glycaemic control and pancreatic β-cell function for type 2 diabetes. | ||
| M28302 | SR1555 | ROR |
| SR1555 is a specific retinoic acid receptor-related orphan nuclear receptor γ (RORγ) inverse agonist with an IC50 value of 1 μM. SR1555 not only inhibits TH17 cell development and function but also increases the frequency of T regulatory cells, as well as inhibits the expression of IL-17. SR1555 can be used for researching autoimmune diseases. | ||
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