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Dorzagliatin

Cat. No. M10047

All AbMole products are for research use only, cannot be used for human consumption.

Dorzagliatin Structure
Synonym:

HMS5552; RO5305552; Sinogliatin

Size Price Availability Quantity
10mM*1mL in DMSO USD 89  USD89 In stock
1mg USD 35  USD35 In stock
5mg USD 85  USD85 In stock
10mg USD 135  USD135 In stock
25mg USD 255  USD255 In stock
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Quality Control & Documentation
Biological Activity

Dorzagliatin (HMS-5552, RO-5305552, Sinogliatin) is a glucokinase (GK) activator, which improves glycaemic control and pancreatic β-cell function for type 2 diabetes.

Chemical Information
Molecular Weight 462.93
Formula C22H27ClN4O5
CAS Number 1191995-00-2
Solubility (25°C) DMSO 93 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Wei Li, et al. Pharmαzιe. Recent clinιcαl advances of glucoκinase activators in the treαtment of diabetes mellitus type 2

[2] Xiao-Xue Zhu, et al. Diabetes Obes Metab. Dorzagliatin (HMS5552), a novel dual-acting glucokinase activator, improves glycaemic control and pancreatic β-cell function in patients with type 2 diabetes: A 28-day treatment study using biomarker-guided patient selection

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Keywords: Dorzagliatin, HMS5552; RO5305552; Sinogliatin supplier, Glucokinase (GK), inhibitors, activators

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