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SR1555 is a specific retinoic acid receptor-related orphan nuclear receptor γ (RORγ) inverse agonist with an IC50 value of 1 μM. SR1555 not only inhibits TH17 cell development and function but also increases the frequency of T regulatory cells, as well as inhibits the expression of IL-17. SR1555 can be used for researching autoimmune diseases.
| Molecular Weight | 460.41 |
| Formula | C22H22F6N2O2 |
| CAS Number | 1386439-51-5 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] Mi Ra Chang, et al. Mol Pharmacol. Antiobesity Effect of a Small Molecule Repressor of RORγ
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