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 About 3 results found for searched term "AG 555" (0.131 seconds)

Cat.No.  Name Target
M20583 AG 555 EGFR/HER2
Tyrphostin B46
AG-555 is an inhibitor of tyrosine kinase , interacts directly with topoisomerase I, thus preventing DNA relaxation. It inhibits EGFR with an IC50 of 0.7 μM.
M10047 Dorzagliatin Glucokinase (GK)
HMS5552; RO5305552; Sinogliatin
Dorzagliatin (HMS-5552, RO-5305552, Sinogliatin) is a glucokinase (GK) activator, which improves glycaemic control and pancreatic β-cell function for type 2 diabetes.
M28302 SR1555  ROR
SR1555 is a specific retinoic acid receptor-related orphan nuclear receptor γ (RORγ) inverse agonist with an IC50 value of 1 μM. SR1555 not only inhibits TH17 cell development and function but also increases the frequency of T regulatory cells, as well as inhibits the expression of IL-17. SR1555 can be used for researching autoimmune diseases.

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