About 6 results found for searched term "AD 01" (0.052 seconds)
Cat.No. | Name | Target |
---|---|---|
M1709 | Everolimus | mTOR |
RAD001, SDZ-RAD, Certican | ||
Everolimus (RAD001) also known as SDZ-RAD and Certican is an mTOR inhibitor with IC50 of 0.63 nM. | ||
M14628 | Elacestrant | Estrogen Receptor |
RAD1901 | ||
Elacestrant (RAD1901) is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. | ||
M14629 | Elacestrant dihydrochloride | Estrogen Receptor |
RAD1901 dihydrochloride | ||
Elacestrant dihydrochloride (RAD1901 dihydrochloride) is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. | ||
M24893 | Mitazalimab | TNF Receptor |
ADC-1013; JNJ-64457107 | ||
Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment. | ||
M25072 | Mipasetamab uzoptirine | TAM Receptor |
ADCT-601 | ||
Mipasetamab uzoptirine (ADCT-601) is an AXL-targeted antibody-drug conjugates (ADCs). Mipasetamab uzoptirine consists of a humanized anti-AXL antibody, a cleavable linker and the potent pyrrolobenzodiazepine (PBD) dimer cytotoxin SG3199. Mipasetamab uzoptirine can be used for the research of cancers. | ||
M51494 | AD 01 | Others |
AD 01, a 24 amino acid peptide of FKBPL (FK506-binding protein like), possesses potent anti-angiogenic activity. |
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