Free shipping on all orders over $ 500

Mipasetamab uzoptirine

Cat. No. M25072

All AbMole products are for research use only, cannot be used for human consumption.

Mipasetamab uzoptirine Structure
Synonym:

ADCT-601

Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Mipasetamab uzoptirine (ADCT-601) is an AXL-targeted antibody-drug conjugates (ADCs). Mipasetamab uzoptirine consists of a humanized anti-AXL antibody, a cleavable linker and the potent pyrrolobenzodiazepine (PBD) dimer cytotoxin SG3199. Mipasetamab uzoptirine can be used for the research of cancers.

Chemical Information
CAS Number 2304799-73-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Francesca Zammarchi, et al. Mol Cancer Ther. Preclinical Development of ADCT-601, a Novel Pyrrolobenzodiazepine Dimer-based Antibody-drυg Conjugate Targeting AXL-expressing Cancers

Related TAM Receptor Products
Axl/Mer/CSF1R-IN-2

Axl/Mer/CSF1R-IN-2 is a Axl, Mer and CSF1R inhibitor.

AXL-IN-15

AXL-IN-15 is a potent Axl inhibitor with both Ki and IC50 <1 nM.

Glesatinib

Glesatinib (MGCD265) is an orally active, potent MET/SMO dual inhibitor. Glesatinib, a tyrosine kinase inhibitor, antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC).

DS-1205b free base 

DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.

Ningetinib Tosylate

Ningetinib Tosylate is a potent, orally bioavailable small molecule tyrosine kinase inhibitor (TKI) with IC50s of 6.7, 1.9 and <1.0 nM for c-Met, VEGFR2 and Axl, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: Mipasetamab uzoptirine, ADCT-601 supplier, TAM Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.