About 12 results found for searched term "9-ing-41" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20731 | Elraglusib | GSK-3 |
| 9-ING-41 | ||
| Elraglusib (9-ING-41) is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with antitumor activity. Elraglusib induces apoptosis and cell cycle arrest at prophase by targeting centrosomes and microtubule-bound GSK3β. | ||
| M11227 | FM-479 | JAK |
| Fm-479 was a negative control of FM-381 and showed no activity against JAK3 or other kinases. Fm-381 is a potent covalent reversible inhibitor of JAK3 targeting unique Cys909. For JAK3, FM-381 was 410, 2700 and 3600 times more selective than JAK1, JAK2 and TYK2 with IC50 of 127 pM. | ||
| M5989 | Tandospirone | 5-HT Receptor |
| SM-3997 | ||
| Tandospirone(SM-3997) is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300-41000 nM). | ||
| M11242 | EI1 | Histone Methyltransferase |
| KB-145943 | ||
| EI1 (KB-145943) is a novel and effective EZH2 inhibitor, capable of acting on EZH2 (WT) and EZH2 (Y641F) with IC50 values of 15 nM and 13 nM, respectively. | ||
| M11243 | CPI-169 | Histone Methyltransferase |
| CPI 169 R-enantiomer | ||
| Cpi-169 (CPI 169 R-Enantiomer) is a novel and effective EZH2 inhibitor, capable of inhibiting the activity of EZH2 WT, EZH2 Y641N and EZH1 with IC50 value of 0.24 nM, respectively. 0.51 nM and 6.1 nM. | ||
| M15031 | Recombinant Mouse FGF-9 (E. coli) | Cytokines and Growth Factors |
| Fibroblast Growth Factor-9; FGF9 | ||
| Fibroblast growth factor-9 (FGF-9) is a multipotent cytokine belonging to the heparin binding FGF family. Like other members of the family, FGF-9 resembles a β -trilobular structure. Fgf-9 [PRO3-SER208 (Ser34Asn)], Accession # P54130. | ||
| M15071 | Recombinant Mouse FGF-9 (E.coli,N-6His) | Cytokines and Growth Factors |
| Fibroblast growth factor 9;FGF-9;Glia-activating factor | ||
| Recombinant mouse fibroblast growth factor 9 was produced by the escherichia coli expression system, and the target gene encoding MET1-SER208 was expressed as 6His at the C-terminal. Accession # : P54130. | ||
| M29240 | DK419 | Wnt/beta-catenin |
| DK419 is a potent and orally active Wnt/β-catenin signaling inhibitor, with an IC50 of 0.19 μM. DK419 reduces protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin and induces production of pAMPK. | ||
| M43973 | A-582941 dihydrochloride | AChR/AChE |
| A-582941 dihydrochloride is a potent, selective, partial agonist of α7 nAChR across the blood-brain barrier, with Ki values of 10.8 nM in rat meninges and 16.7 nM in human frontal cortex.Additionally, A-582941 dihydrochloride binds to human 5- and 5HT3 receptors with a Ki value of 150 nM. In addition, A-582941 dihydrochloride can bind to human 5- HT3 receptors at a Ki value of 150 nM. A-582941 dihydrochloride can be used in studies of various neurodegenerative diseases and cognitive deficits. | ||
| M51291 | Thymopoietin i/ii (29-41) (bovine) | Others |
| Thymopoietin i/ii (29-41) (bovine) is a peptide corresponding to positions 29-41 of bovine thymopoietin II. | ||
| M53440 | CEF6 | Anti-infection |
| CEF6 is a 9-aa-long peptide corresponding to aa 418-426 of the influenza A virus (H1N1) nucleocapsid protein. | ||
| M54655 | K41498 TFA | CRFR |
| K41498 TFA is an antisauvagine-30 (aSvg-30) analog and a strongly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM, and 425 nM for human CRF2α, CRF2β, and CRF1 receptors, respectively.K41498 TFA inhibits sauvagine-stimulated cAMP accumulation in hCRF2α/hCRF2β expressing cells. K41498 TFA can be used in hypotension studies. | ||
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